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TRAF family member-associated NF-kappa-B activator

Summary

UniProt ID

P70347

Gene Symbol

Itraf
Tank

Gene ID

21353

Organism

Mus musculus (house mouse)

External Links

GlyGen: P70347
PubChem: P70347
O-GlcNAcAtlas: P70347
Re-Glyco: P70347

Annotation

Keyword

Alternative splicing
Coiled coil
Cytoplasm
DNA damage
Phosphoprotein
Reference proteome
Zinc-finger

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
protein-containing complex
cytosol

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
positive regulation of protein deubiquitination
positive regulation of type I interferon production
negative regulation of canonical NF-kappaB signal transduction
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to ionizing radiation
positive regulation of ubiquitin-specific protease activity
DNA damage response
negative regulation of tumor necrosis factor-mediated signaling pathway

Displaying **all 6** entries
GO Term
cysteine-type deubiquitinase activity
ubiquitin protein ligase binding
molecular adaptor activity
molecular function inhibitor activity
metal ion binding
deubiquitinase activator activity

Annotation information from UniProt.

Sequence

MSLKRHSLRRNACHLETRAGIPTILYSDATGQRGMDKNIGEQLNRAYEAFRQACMDRDSAVRELQQKQTENYEQRIREQQEQLSFQQNLIDRLKSQLLLVDSSRDNSYGYVPLLEDSDRRKNNLTLDEPHDKVKLGTLRDKQSKVRRQEVSSGKESAKGLNIPLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDTQCSVPIQCTDKTEKQEALFKPQAKDDINRGMSCVTAVTPRGLGRDEEDTSFESLSKFNVKFPPMDNDSIFLHSTPEAPSILAPATPETVCQDRFNMEVRDNPGNFVKTEETLFEIQGIDPITSAIQNLKTTDKTNPSNLRATCLPAGDHNVFYVNTFPLQDPPDAPFPSLDSPGKAVRGPQQPFWKPFLNQDTDLVVPSDSDSELLKPLVCEFCQELFPPSITSRGDFLRHLNTHFNGET

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites