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MIRAGE
Nuclear receptor coactivator 1
Summary
- UniProt ID
- P70365
- Gene Symbol
-
- Ncoa1
- Src1
- Gene ID
- 17977
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Acyltransferase
- Alternative splicing
- Direct protein sequencing
- Isopeptide bond
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Transcription regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| chromatin |
| plasma membrane |
| nucleoplasm |
| cytosol |
| transcription regulator complex |
| RNA polymerase II transcription regulator complex |
Sequence
MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRMLIHPPEDPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDSNSGMSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARVNRQQSSDLNSSSSHTNSSNNQGNFGCSPGNQIVANVALNQGQAGSQSSNPSLNLNNSPMEGTGIALSQFMSPRRQANSGLATRARMSNNSFPPNIPTLSSPVGITSGACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDSKEIASILNEMIQSDNSDNSANEGKPLDSGLLHNNDRLSEGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSVPASTAVSVSGQSQGSASIKLELDAAKKKESKDHQLLRYLLDKDEKDLRSTPNLCLDDVKVKVEKKEQMDPCNTNPTPMTKPAPEEVKLESQSQFTADLDQFDQLLPTLEKAAQLPSLCETDRMDGAVTGVSIKAEVLPASLQPTTARAAPRLSRLPELELEAIDNQFGQPGAGDQIPWANNTLTTINQNKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSERFPPQQATPPLMMEDRPTLYSQPYSSPSPTAGLSGPFQGMVRQKPSLGAMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQAILNQFAANAPVGMNMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQIIQQQRAMLMRHQSFGNNIPPSSGLPVQMGTPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLATRSSMVNRGMAGNMGGQFGAGISPQMQQNVFQYPGPGLVPQGEATFAPSLSPGSSMVPMPVPPPQSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQSQPAPAQPGVYNNMSITVSMAGGNANIQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSSTDLLKTDADGNQQVQQVQVFADVQCTVNLVGGDPYLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 389 |
|
|||
| 401 |
|
|||
| 642 |
|
|||
| 643 |
|
|||
| 644 |
|
|||
| 985 |
|
|
||
| 1007 |
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cytoprotection by HMOX1 | Mus musculus |
| Endogenous sterols | Mus musculus |
| Estrogen-dependent gene expression | Mus musculus |
| HATs acetylate histones | Mus musculus |
| LXRs regulate gene expression linked to cholesterol transport and efflux | Mus musculus |
| LXRs regulate gene expression to control bile acid homeostasis | Mus musculus |
| Recycling of bile acids and salts | Mus musculus |
| Regulation of lipid metabolism by PPARalpha | Mus musculus |
| SUMOylation of transcription cofactors | Mus musculus |
| Synthesis of bile acids and bile salts | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11633 | thyroid hormone resistance syndrome | |
| DOID:9970 | obesity |
