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Sodium/calcium exchanger 1

Summary

UniProt ID

P70414

Gene Symbol

Slc8a1
Ncx

Organism

Mus musculus (house mouse)

External Links

PubChem: P70414

Annotation

Keyword

Antiport
Calcium transport
Calmodulin-binding
Cell membrane
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Sodium transport
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 38 in total

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GO Term
calcium ion homeostasis
cardiac muscle contraction
negative regulation of protein serine/threonine kinase activity
cell communication by electrical coupling involved in cardiac conduction
relaxation of smooth muscle
heart morphogenesis
positive regulation of cytosolic calcium ion concentration
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
vascular associated smooth muscle contraction
response to ATP

Displaying entries **1 - 10** of 19 in total

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GO Term
postsynapse
microtubule
intercalated disc
dendritic spine
dendritic shaft
axon terminus
postsynaptic density
basolateral plasma membrane
Z disc
T-tubule

Displaying **all 7** entries
GO Term
calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration
monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential
calmodulin binding
ankyrin binding
transmembrane transporter binding
calcium:sodium antiporter activity
calcium ion binding

Annotation information from UniProt.

Sequence

MLRLSLPPNVSMGFRLVALVALLFSHVDHITADTEAETGGNETTECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPASKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNMEMAENDPVSKIFFEQGTYQCLENCGTVALTIMRRGGDLSTTVFVDFRTEDGTANAASDYEFTEGTVIFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVRVSSDVSEDGILESNHASSIACLGSPSTATITIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIIPYKTIEGTARGGGEDFEDTCGEPEFQNDEIVKTISVKVIDDEEYEKNKTFFIEIGEPRLVEMSEKKALLLNELGGFTLTGKEMYGQPIFRKVHARDHPIPSTVITISEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIQESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSSLFVLLWLLYIFFSSLEAYCHIKGF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
41	N-linked (GlcNAc...) asparagine			UniProt
157	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Ion homeostasis	Mus musculus
Reduction of cytosolic Ca++ levels	Mus musculus
Sodium/Calcium exchangers	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements