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Receptor tyrosine-protein kinase erbB-2

Summary

UniProt ID

P70424

Gene Symbol

Erbb2
Kiaa3023
Neu

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003777
PubChem: P70424

Annotation

Keyword

ATP-binding
Activator
Cell membrane
Cell projection
Cytoplasm
Disulfide bond
Endosome
Glycoprotein
Nucleus
Phosphoprotein
Receptor
Reference proteome
Signal
Transcription regulation
Transmembrane helix
Tyrosine-protein kinase

Gene Ontology (GO)

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GO Term
neuromuscular junction development
motor neuron axon guidance
cell surface receptor signaling pathway
nervous system development
peripheral nervous system development
positive regulation of cell population proliferation
glial cell differentiation
positive regulation of gene expression
Schwann cell development
neurogenesis

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GO Term
nucleoplasm
early endosome
cytosol
basal plasma membrane
basolateral plasma membrane
apical plasma membrane
perinuclear region of cytoplasm
cytoplasm
plasma membrane
microvillus

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GO Term
RNA polymerase I core binding
ErbB-3 class receptor binding
transmembrane receptor protein tyrosine kinase activity
ATP binding
coreceptor activity
growth factor binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
identical protein binding
protein-containing complex binding

Annotation information from UniProt.

Sequence

MELAAWCRWGFLLALLSPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPANASLSFLQDIQEVQGYMLIAHNRVKHVPLQRLRIVRGTQLFEDKYALAVLDNRDPLDNVTTAAPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVLRKNNQLAPVDMDTNRSRACPPCAPTCKDNHCWGESPEDCQILTGTICTSGCARCKGRLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALITYNTDTFESMLNPEGRYTFGASCVTTCPYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCAGVCYGLGMEHLRGARAITSDNIQEFAGCKKIFGSLAFLPESFDGNPSSGVAPLKPEHLQVFETLEEITGYLYISAWPESFQDLSVFQNLRVIRGRILHDGAYSLTLQGLGIHSLGLRSLRELGSGLALIHRNTHLCFVNTVPWDQLFRNPHQALLHSGNRPEEACGLEGLVCNSLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVWKGLPREYVRGKHCLPCHPECQPQNSSETCYGSEADQCEACAHYKDSSSCVARCPSGVKPDLSYMPIWKYPDEEGICQPCPINCTHSCVDLDERGCPAEQRASPVTFIIATVVGVLLFLIIVVVIGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAVPNQAQMRILKETELRKLKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLEDDDMGELVDAEEYLVPQQGFFSPDPALGTGSTAHRRHRSSSARSGGGELTLGLEPSEEEPPRSPLAPSEGAGSDVFDGDLAVGVTKGLQSLSPHDLSPLQRYSEDPTLPLPPETDGYVAPLACSPQPEYVNQPEVRPQSPLTPEGPPPPIRPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAPRAGTASQPHPSPAFSPAFDNLYYWDQNSSEQGPPPSTFEGTPTAENPEYLGLDVPV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
68	N-linked (GlcNAc...) asparagine	UniProt
125	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
188	N-linked (GlcNAc...) asparagine	UniProt
260	N-linked (GlcNAc...) asparagine	UniProt
531	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
572	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
630	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
RAF/MAP kinase cascade	Mus musculus
SHC1 events in ERBB2 signaling	Mus musculus
Sema4D induced cell migration and growth-cone collapse	Mus musculus
Signaling by ERBB2	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

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Annotation

International Collaboration

Acknowledgements