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MIRAGE
Protein smoothened
Summary
- UniProt ID
- P91682
- Gene Symbol
-
- CG11561
- smo
- Gene ID
- 33196
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cell projection
- Developmental protein
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| cilium |
| dendrite |
| neuronal cell body |
Sequence
MQYLNFPRMPNIMMFLEVAILCLWVVADASASSAKFGSTTPASAQQSDVELEPINGTLNYRLYAKKGRDDKPWFDGLDSRHIQCVRRARCYPTSNATNTCFGSKLPYELSSLDLTDFHTEKELNDKLNDYYALKHVPKCWAAIQPFLCAVFKPKCEKINGEDMVYLPSYEMCRITMEPCRILYNTTFFPKFLRCNETLFPTKCTNGARGMKFNGTGQCLSPLVPTDTSASYYPGIEGCGVRCKDPLYTDDEHRQIHKLIGWAGSICLLSNLFVVSTFFIDWKNANKYPAVIVFYINLCFLIACVGWLLQFTSGSREDIVCRKDGTLRHSEPTAGENLSCIVIFVLVYYFLTAGMVWFVFLTYAWHWRAMGHVQDRIDKKGSYFHLVAWSLPLVLTITTMAFSEVDGNSIVGICFVGYINHSMRAGLLLGPLCGVILIGGYFITRGMVMLFGLKHFANDIKSTSASNKIHLIIMRMGVCALLTLVFILVAIACHVTEFRHADEWAQSFRQFIICKISSVFEEKSSCRIENRPSVGVLQLHLLCLFSSGIVMSTWCWTPSSIETWKRYIRKKCGKEVVEEVKMPKHKVIAQTWAKRKDFEDKGRLSITLYNTHTDPVGLNFDVNDLNSSETNDISSTWAAYLPQCVKRRMALTGAATGNSSSHGPRKNSLDSEISVSVRHVSVESRRNSVDSQVSVKIAEMKTKVASRSRGKHGGSSSNRRTQRRRDYIAAATGKSSRRRESSTSVESQVIALKKTTYPNASHKVGVFAHHSSKKQHNYTSSMKRRTANAGLDPSILNEFLQKNGDFIFPFLQNQDMSSSSEEDNSRASQKIQDLNVVVKQQEISEDDHDGIKIEELPNSKQVALENFLKNIKKSNESNSNRHSRNSARSQSKKSQKRHLKNPAADLDFRKDCVKYRSNDSLSCSSEELDVALDVGSLLNSSFSGISMGKPHSRNSKTSCDVGIQANPFELVPSYGEDELQQAMRLLNAASRQRTEAANEDFGGTELQGLLGHSHRHQREPTFMSESDKLKMLLLPSK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 55 | N-linked (GlcNAc...) asparagine |
|
||
| 95 | N-linked (GlcNAc...) asparagine |
|
||
| 184 | N-linked (GlcNAc...) asparagine |
|
||
| 195 | N-linked (GlcNAc...) asparagine |
|
||
| 213 | N-linked (GlcNAc...) asparagine |
|
||
| 336 | N-linked (GlcNAc...) asparagine |
|
||
| 419 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of CI | Drosophila melanogaster |
| Activation of SMO | Drosophila melanogaster |
| Activation of SMO | Drosophila melanogaster |
| Assembly of the 'signalling complexes' | Drosophila melanogaster |
| Hedgehog 'off' state | Drosophila melanogaster |
| Phosphorylation of SMO | Drosophila melanogaster |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050338 | primary bacterial infectious disease |
