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Tyrosine-protein phosphatase non-receptor type substrate 1

Summary

UniProt ID

P97797

Gene Symbol

Sirpa
Bit
Myd1
Ptpns1
Shps1
Sirp

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003822

GlyConnect

2714

GlyGen

P97797

PubChem

P97797

The O-GlcNAc Database

P97797

RaftProt

P97797

O-GlcNAcAtlas

P97797

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Reference proteome
Repeat
SH3-binding
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **11 - 20** of 32 in total

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GO Term
negative regulation of tumor necrosis factor production
negative regulation of nitric oxide biosynthetic process
regulation of nitric oxide biosynthetic process
negative regulation of phagocytosis
positive regulation of phagocytosis
positive regulation of T cell activation
granulocyte migration
negative regulation of cytokine production involved in inflammatory response
negative regulation of I-kappaB phosphorylation
cellular response to type II interferon

Displaying **all 2** entries
GO Term
cell surface
plasma membrane

Displaying **all 6** entries
GO Term
SH3 domain binding
protein tyrosine kinase binding
protein phosphorylated amino acid binding
protein phosphatase binding
GTPase regulator activity
protein binding involved in heterotypic cell-cell adhesion

Annotation information from UniProt.

Sequence

MEPAGPAPGRLGPLLLCLLLSASCFCTGATGKELKVTQPEKSVSVAAGDSTVLNCTLTSLLPVGPIRWYRGVGPSRLLIYSFAGEYVPRIRNVSDTTKRNNMDFSIRISNVTPADAGIYYCVKFQKGSSEPDTEIQSGGGTEVYVLAKPSPPEVSGPADRGIPDQKVNFTCKSHGFSPRNITLKWFKDGQELHPLETTVNPSGKNVSYNISSTVRVVLNSMDVNSKVICEVAHITLDRSPLRGIANLSNFIRVSPTVKVTQQSPTSMNQVNLTCRAERFYPEDLQLIWLENGNVSRNDTPKNLTKNTDGTYNYTSLFLVNSSAHREDVVFTCQVKHDQQPAITRNHTVLGFAHSSDQGSMQTFPDNNATHNWNVFIGVGVACALLVVLLMAALYLLRIKQKKAKGSTSSTRLHEPEKNAREITQVQSLIQDTNDINDITYADLNLPKEKKPAPRAPEPNNHTEYASIETGKVPRPEDTLTYADLDMVHLSRAQPAPKPEPSFSEYASVQVQRK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 22 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
54	N-linked (GlcNAc...) asparagine		G23863VK G50045TK G02815KT G06110VR G66538GV	UniProt GlyGen GlyConnect
92	N-linked (GlcNAc...) asparagine		G80223IX G10773YW G46902YN G65092SV G23863VK G84820NF G50045TK G82119TF G05724UK G33609NS G39188ZX G25637MV G23453IV G02815KT G06110VR G00406II G60145BJ G66538GV G74724QE G14669DU G63628AV G32550BI G71838YU	UniProt GlyGen GlyConnect
110			G80223IX G23863VK G45504EY G50045TK G82119TF G94854LT G06110VR G66538GV G74724QE G14669DU G63628AV G32550BI G89753LT	GlyGen GlyConnect
168	N-linked (GlcNAc...) asparagine		G46902YN G84820NF G50045TK G72735IY G33609NS G39188ZX G23453IV G57776ZU G06110VR G66538GV G14669DU G63628AV G71838YU	GlycoProtDB UniProt GlyGen GlyConnect
170			G49108TO	GlyGen The O-GlcNAc Database
180	N-linked (GlcNAc...) asparagine		G07755XJ	UniProt GlyGen
205	N-linked (GlcNAc...) asparagine		G63980BQ G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
209	N-linked (GlcNAc...) asparagine		G25541YH G57292HF G76329HL	GlycoProtDB UniProt GlyGen GlyConnect
246	N-linked (GlcNAc...) asparagine	16944957	G50045TK G72735IY G05724UK G31852PQ G33609NS G39188ZX G06110VR G66538GV G14669DU G63628AV G32550BI	GlycoProtDB UniProt GlyGen GlyConnect
248			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Cell surface interactions at the vascular wall	Mus musculus
Neutrophil degranulation	Mus musculus
Signal regulatory protein family interactions	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements