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MIRAGE
Indian hedgehog protein
Summary
- UniProt ID
- P97812
- Gene Symbol
-
- Ihh
- Gene ID
- 16147
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Autocatalytic cleavage
- Calcium
- Cell membrane
- Developmental protein
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Metal-binding
- Palmitate
- Protease
- Reference proteome
- Secreted
- Signal
- Transferase
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| extracellular matrix |
| Golgi membrane |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| patched binding |
| very-low-density lipoprotein particle binding |
| cholesterol-protein transferase activity |
| calcium ion binding |
| peptidase activity |
Sequence
MSPAWLRPRLRFCLFLLLLLLVPAARGCGPGRVVGSRRRPPRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAAAKTGGCFPAGAQVRLENGERVALSAVKPGDRVLAMGEDGTPTFSDVLIFLDREPNRLRAFQVIETQDPPRRLALTPAHLLFIADNHTEPAAHFRATFASHVQPGQYVLVSGVPGLQPARVAAVSTHVALGSYAPLTRHGTLVVEDVVASCFAAVADHHLAQLAFWPLRLFPSLAWGSWTPSEGVHWYPQMLYRLGRLLLEESTFHPLGMSGAGS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 282 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of SMO | Mus musculus |
| Hedgehog ligand biogenesis | Mus musculus |
| Ligand-receptor interactions | Mus musculus |
| Release of Hh-Np from the secreting cell | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060850 | annular pancreas | |
| DOID:0110964 | brachydactyly type A1 | |
| DOID:10487 | Hirschsprung's disease |
