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A disintegrin and metalloproteinase with thrombospondin motifs 1

Summary

UniProt ID

P97857

Gene Symbol

Adamts1

Gene ID

11504

Organism

Mus musculus (house mouse)

External Links

GlyGen: P97857
The O-GlcNAc Database: P97857
Re-Glyco: P97857

Annotation

Keyword

Calcium
Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Heparin-binding
Metal-binding
Metalloprotease
Reference proteome
Repeat
Signal
Zinc
Zymogen

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
extracellular region
basement membrane
extracellular matrix
cytoplasmic vesicle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
positive regulation of G1/S transition of mitotic cell cycle
ovulation from ovarian follicle
kidney development
heart trabecula formation
positive regulation of vascular associated smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration
proteolysis
negative regulation of angiogenesis
extracellular matrix organization

Displaying **all 3** entries
GO Term
heparin binding
zinc ion binding
metalloendopeptidase activity

Annotation information from UniProt.

Sequence

MQPKVPLGSRKQKPCSDMGDVQRAARSRGSLSAHMLLLLLASITMLLCARGAHGRPTEEDEELVLPSLERAPGHDSTTTRLRLDAFGQQLHLKLQPDSGFLAPGFTLQTVGRSPGSEAQHLDPTGDLAHCFYSGTVNGDPGSAAALSLCEGVRGAFYLQGEEFFIQPAPGVATERLAPAVPEEESSARPQFHILRRRRRGSGGAKCGVMDDETLPTSDSRPESQNTRNQWPVRDPTPQDAGKPSGPGSIRKKRFVSSPRYVETMLVADQSMADFHGSGLKHYLLTLFSVAARFYKHPSIRNSISLVVVKILVIYEEQKGPEVTSNAALTLRNFCSWQKQHNSPSDRDPEHYDTAILFTRQDLCGSHTCDTLGMADVGTVCDPSRSCSVIEDDGLQAAFTTAHELGHVFNMPHDDAKHCASLNGVSGDSHLMASMLSSLDHSQPWSPCSAYMVTSFLDNGHGECLMDKPQNPIKLPSDLPGTLYDANRQCQFTFGEESKHCPDAASTCTTLWCTGTSGGLLVCQTKHFPWADGTSCGEGKWCVSGKCVNKTDMKHFATPVHGSWGPWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNIEDCPDNNGKTFREEQCEAHNEFSKASFGNEPTVEWTPKYAGVSPKDRCKLTCEAKGIGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTCKKMSGIVTSTRPGYHDIVTIPAGATNIEVKHRNQRGSRNNGSFLAIRAADGTYILNGNFTLSTLEQDLTYKGTVLRYSGSSAALERIRSFSPLKEPLTIQVLMVGHALRPKIKFTYFMKKKTESFNAIPTFSEWVIEEWGECSKTCGSGWQRRVVQCRDINGHPASECAKEVKPASTRPCADLPCPHWQVGDWSPCSKTCGKGYKKRTLKCVSHDGGVLSNESCDPLKKPKHYIDFCTLTQCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	GlyTouCan ID	Source
458			GlyGen
548	N-linked (GlcNAc...) asparagine		UniProt GlyGen
721	N-linked (GlcNAc...) asparagine		UniProt GlyGen
723		G49108TO	The O-GlcNAc Database
724		G49108TO	The O-GlcNAc Database
765	N-linked (GlcNAc...) asparagine		UniProt GlyGen
783	N-linked (GlcNAc...) asparagine		UniProt GlyGen
794		G49108TO	The O-GlcNAc Database
946	N-linked (GlcNAc...) asparagine		UniProt GlyGen