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MIRAGE
Mannan-binding lectin serine protease 1
Summary
- UniProt ID
- P98064
- Gene Symbol
-
- Crarf
- Masp1
- Masp3
- Gene ID
- 17174
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003836
- PubChem
- P98064
- Re-Glyco
- P98064
Annotation
- Keyword
-
- Alternative splicing
- Autocatalytic cleavage
- Calcium
- Complement activation lectin pathway
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Hydroxylation
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| nucleoplasm |
| cytosol |
| extracellular space |
| GO Term |
|---|
| complement activation, lectin pathway |
| proteolysis |
| GO Term |
|---|
| calcium-dependent protein binding |
| serine-type endopeptidase activity |
| calcium ion binding |
| protein homodimerization activity |
Sequence
MRFLSFWRLLLYHALCLALPEVSAHTVELNEMFGQIQSPGYPDSYPSDSEVTWNITVPEGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGTFMSVTFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSGNLFTQRTGTITSPDYPNPYPKSSECSYTIDLEEGFMVSLQFEDIFDIEDHPEVPCPYDYIKIKAGSKVWGPFCGEKSPEPISTQTHSVQILFRSDNSGENRGWRLSYRAAGNECPKLQPPVYGKIEPSQAVYSFKDQVLVSCDTGYKVLKDNEVMDTFQIECLKDGAWSNKIPTCKIVDCGAPAGLKHGLVTFSTRNNLTTYKSEIRYSCQQPYYKMLHNTTGVYTCSAHGTWTNEVLKRSLPTCLPVCGVPKFSRKQISRIFNGRPAQKGTMPWIAMLSHLNGQPFCGGSLLGSNWVLTAAHCLHQSLDPEEPTLHSSYLLSPSDFKIIMGKHWRRRSDEDEQHLHVKRTTLHPLYNPSTFENDLGLVELSESPRLNDFVMPVCLPEQPSTEGTMVIVSGWGKQFLQRFPENLMEIEIPIVNSDTCQEAYTPLKKKVTKDMICAGEKEGGKDACAGDSGGPMVTKDAERDQWYLVGVVSWGEDCGKKDRYGVYSYIYPNKDWIQRITGVRN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 54 | N-linked (GlcNAc...) asparagine |
|
||
| 183 | N-linked (GlcNAc...) asparagine |
|
||
| 390 | N-linked (GlcNAc...) asparagine |
|
||
| 412 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Mus musculus |
| Initial triggering of complement | Mus musculus |
| Lectin pathway of complement activation | Mus musculus |
| Scavenging by Class A Receptors | Mus musculus |
