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Disabled homolog 2

Summary

UniProt ID

P98078

Gene Symbol

Dab2
Doc2

Organism

Mus musculus (house mouse)

External Links

GlyGen: P98078
PubChem: P98078
The Human Metabolome Database: HMDBP14539
O-GlcNAcAtlas: P98078

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Apoptosis
Coated pit
Cytoplasm
Cytoplasmic vesicle
Developmental protein
Differentiation
Endocytosis
Nucleus
Phosphoprotein
Protein transport
Reference proteome
Wnt signaling pathway

Gene Ontology (GO)

Displaying entries **11 - 20** of 34 in total

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GO Term
renal protein absorption
cell morphogenesis
positive regulation of receptor recycling
positive regulation of receptor internalization
receptor-mediated endocytosis
positive regulation of epithelial to mesenchymal transition
clathrin coat assembly
negative regulation of ERK1 and ERK2 cascade
hematopoietic stem cell proliferation
cellular response to transforming growth factor beta stimulus

Displaying **all 9** entries
GO Term
nucleus
cytoplasm
plasma membrane
intracellular membrane-bounded organelle
clathrin-coated pit
clathrin coat of coated pit
clathrin-coated vesicle membrane
apical plasma membrane
perinuclear region of cytoplasm

Displaying **all 8** entries
GO Term
integrin binding
phosphatidylinositol-4,5-bisphosphate binding
clathrin binding
phosphatidylinositol binding
AP-2 adaptor complex binding
cargo receptor activity
low-density lipoprotein particle receptor binding
clathrin adaptor activity

Annotation information from UniProt.

Sequence

MSNEVETSTTNGQPDQQAAPKAPSKKEKKKGSEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEDKKKVEEANKAEENGSEALMTLDDQANKLKLGVDQMDLFGDMSTPPDLNSPTESKDILLVDLNSEIDTNQNSLRENPFLTNGVTSCSLPRPKPQASFLPENAFSANLNFFPTPNPDPFRDDPFAQPDQSAPSSFDSLTSPDQKKASLSSSSTPQSKGPLNGDTDYFGQQFDQLSNRTGKPEAQGGPWPYPSSQTQQAVRTQNGVSEREQNGFHIKSSPNPFVGSPPKGLSVPNGVKQDLESSVQSSAHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFASEPPGQMSPTGQPAVPQSNFLDLFKGNAPAPVGPLVGLGTVPVTPPQAGPWTPVVYSPSTTVVPGAIISGQPPSFRQPLVFGTTPAVQVWNQSPSFATPASPPPPTVWCPTTSVAPNAWSSTSPLGNPFQSNNIFPPPTMSTQSSPQPMMSSVLATPPQPPPRNGPLKDIPSDAFTGLDPLGDKEVKEVKEMFKDFQLRQPPLVPSRKGETPPSGTSSAFSSYFNNKVGIPQEHVDHDDFDANQLLNKINEPPKPAPRQGVLLGTKSADNSLENPFSKGFSSSNPSVVSQPASSDPHRSPFGNPFA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	GlyTouCan ID	Source
423	G49108TO	GlyGen
504		GlyGen
558		GlyGen
566		GlyGen
737	G49108TO	GlyGen
749	G49108TO	GlyGen
753	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Mus musculus
Clathrin-mediated endocytosis	Mus musculus
Formation of annular gap junctions	Mus musculus
Gap junction degradation	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements