Coagulation factor XII

Summary
UniProt ID
P98140
Gene Symbol
  • F12
Organism
Bos taurus (domestic cattle)
PubChem
P98140
Annotation
Keyword
  • Direct protein sequencing
  • Disulfide bond
  • EGF-like domain
  • Fibrinolysis
  • Glycoprotein
  • Kringle
  • Reference proteome
  • Repeat
  • Secreted
  • Serine protease
  • Signal
  • Zymogen
Gene Ontology (GO)
Displaying all 3 entries
GO Term
blood coagulation
fibrinolysis
zymogen activation
Displaying all 2 entries
GO Term
rough endoplasmic reticulum
extracellular space
Displaying all 2 entries
GO Term
serine-type endopeptidase activity
calcium ion binding
Sequence
MRALLLLGALLVSLESTVSTPPWKGPKKHKLTDSEHTVVLTVTGEPCHFPFQYHRQLHHKCIHRGRPGPRPWCATTPNFEKDQRWAYCLEPKKVKDHCSKHNPCQKGGTCVNMPDGPRCICADHFTGKHCQKEKCFEPQFFRFFHENEIWHRLEPAGVVKCQCKGPNAQCKPLASQVCRTNPCLNGGSCLQAEGHRLCRCAPSFAGRLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAPCQSWASEATYWNVTAEQVLNWGLGDHAFCRASTPPRGYRNPDNDTRPLCFIWKGDRLSWNYCRLAPCQAAAGHEHFPLPSPSALQKPESTTQTPLPSLTSGWCSPTPLASGGPGGCGQRLRKWLSSLNRVVGGLVALPGAHPYIAALYWDQHFCAGSLIAPCWVLTAAHCLQNRPAPKELTVVLGQDRHNQSCEQCQTLAVRDYRLHEAFSPITYQHDLALVRLQESADGCCAHPSPFVQPVCLPSTAARPAESEAAVCEVAGWGHQFEGGEYSSFLQEAQVPLIDPQRCSAPDVHGAAFTQGMLCAGFLEGGTDACQGDSGGPLVCEDETPERQLILRGIVSWGSGCGNRLKPGVYTDVANYLAWIREHTAS
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
109 O-linked (Fuc) threonine
251 N-linked (GlcNAc...) asparagine
282 N-linked (GlcNAc...) asparagine
429 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024