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Apolipoprotein A-I

Summary

UniProt ID

Q00623

Gene Symbol

Apoa1

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q00623
PubChem: Q00623
The O-GlcNAc Database: Q00623
RaftProt: Q00623

Annotation

Keyword

3D-structure
Cholesterol metabolism
Direct protein sequencing
Glycoprotein
HDL
Lipid transport
Oxidation
Palmitate
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal

Gene Ontology (GO)

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GO Term
protein stabilization
positive regulation of stress fiber assembly
acylglycerol homeostasis
phospholipid homeostasis
negative regulation of cell adhesion molecule production
cholesterol import
protein oxidation
peptidyl-methionine modification
regulation of intestinal cholesterol absorption
reverse cholesterol transport

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GO Term
extracellular region
extracellular space
endocytic vesicle
extracellular vesicle
cytosol
cell surface
very-low-density lipoprotein particle
low-density lipoprotein particle
intermediate-density lipoprotein particle
high-density lipoprotein particle

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GO Term
phosphatidylcholine-sterol O-acyltransferase activator activity
cholesterol binding
heat shock protein binding
cholesterol transfer activity
identical protein binding
protein homodimerization activity
chemorepellent activity
amyloid-beta binding
phospholipid binding
lipase inhibitor activity

Annotation information from UniProt.

Sequence

MKAVVLAVALVFLTGSQAWHVWQQDEPQSQWDKVKDFANVYVDAVKDSGRDYVSQFESSSLGQQLNLNLLENWDTLGSTVSQLQERLGPLTRDFWDNLEKETDWVRQEMNKDLEEVKQKVQPYLDEFQKKWKEDVELYRQKVAPLGAELQESARQKLQELQGRLSPVAEEFRDRMRTHVDSLRTQLAPHSEQMRESLAQRLAELKSNPTLNEYHTRAKTHLKTLGEKARPALEDLRHSLMPMLETLKTQVQSVIDKASETLTAQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
ABC transporters in lipid homeostasis	Mus musculus
Chylomicron assembly	Mus musculus
Chylomicron remodeling	Mus musculus
HDL assembly	Mus musculus
HDL clearance	Mus musculus
HDL remodeling	Mus musculus
Heme signaling	Mus musculus
Platelet degranulation	Mus musculus
Post-translational protein phosphorylation	Mus musculus
Regulation of IGF Activity by IGFBP	Mus musculus