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Apolipoprotein A-I

Summary

UniProt ID

Q00623

Gene Symbol

Apoa1

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q00623
PubChem: Q00623
The O-GlcNAc Database: Q00623
RaftProt: Q00623

Annotation

Keyword

3D-structure
Cholesterol metabolism
Direct protein sequencing
Glycoprotein
HDL
Lipid transport
Oxidation
Palmitate
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal

Gene Ontology (GO)

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GO Term
positive regulation of Rho protein signal transduction
triglyceride homeostasis
regulation of protein phosphorylation
endothelial cell proliferation
negative regulation of cytokine production involved in immune response
G protein-coupled receptor signaling pathway
glucocorticoid metabolic process
negative regulation of inflammatory response
adrenal gland development
animal organ regeneration

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GO Term
cytosol
cell surface
very-low-density lipoprotein particle
low-density lipoprotein particle
intermediate-density lipoprotein particle
high-density lipoprotein particle
discoidal high-density lipoprotein particle
spherical high-density lipoprotein particle
chylomicron
extracellular region

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GO Term
phosphatidylcholine-sterol O-acyltransferase activator activity
cholesterol binding
heat shock protein binding
cholesterol transfer activity
identical protein binding
protein homodimerization activity
chemorepellent activity
amyloid-beta binding
phospholipid binding
lipase inhibitor activity

Annotation information from UniProt.

Sequence

MKAVVLAVALVFLTGSQAWHVWQQDEPQSQWDKVKDFANVYVDAVKDSGRDYVSQFESSSLGQQLNLNLLENWDTLGSTVSQLQERLGPLTRDFWDNLEKETDWVRQEMNKDLEEVKQKVQPYLDEFQKKWKEDVELYRQKVAPLGAELQESARQKLQELQGRLSPVAEEFRDRMRTHVDSLRTQLAPHSEQMRESLAQRLAELKSNPTLNEYHTRAKTHLKTLGEKARPALEDLRHSLMPMLETLKTQVQSVIDKASETLTAQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Retinoid metabolism and transport	Mus musculus
Scavenging by Class A Receptors	Mus musculus
Scavenging by Class B Receptors	Mus musculus
Scavenging of heme from plasma	Mus musculus