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Epidermal growth factor receptor

Summary

UniProt ID

Q01279

Gene Symbol

Egfr

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003854

GlyConnect

2297

GlyGen

Q01279

PubChem

Q01279

Annotation

Keyword

ATP-binding
Cell membrane
Developmental protein
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Hydroxylation
Isopeptide bond
Methylation
Nucleus
Palmitate
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of protein catabolic process
positive regulation of DNA replication
positive regulation of vasoconstriction
regulation of JNK cascade
positive regulation of smooth muscle cell proliferation
cellular response to cadmium ion
cellular response to epidermal growth factor stimulus
cellular response to estradiol stimulus

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GO Term
plasma membrane
cell junction
nuclear membrane
receptor complex
membrane raft
multivesicular body, internal vesicle lumen
early endosome membrane
ruffle membrane

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GO Term
transmembrane receptor protein tyrosine kinase activity
epidermal growth factor receptor activity
integrin binding
calmodulin binding
ATP binding
protein kinase binding
protein phosphatase binding
ubiquitin protein ligase binding
identical protein binding
protein-containing complex binding

Annotation information from UniProt.

Sequence

MRPSGTARTTLLVLLTALCAAGGALEEKKVCQGTSNRLTQLGTFEDHFLSLQRMYNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALYENTYALAILSNYGTNRTGLRELPMRNLQEILIGAVRFSNNPILCNMDTIQWRDIVQNVFMSNMSMDLQSHPSSCPKCDPSCPNGSCWGGGEENCQKLTKIICAQQCSHRCRGRSPSDCCHNQCAAGCTGPRESDCLVCQKFQDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVEEDGIRKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFKGDSFTRTPPLDPRELEILKTVKEITGFLLIQAWPDNWTDLHAFENLEIIRGRTKQHGQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFGTPNQKTKIMNNRAEKDCKAVNHVCNPLCSSEGCWGPEPRDCVSCQNVSRGRECVEKCNILEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGIMGENNTLVWKYADANNVCHLCHANCTYGCAGPGLQGCEVWPSGPKIPSIATGIVGGLLFIVVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASDISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQQGFFNSPSTSRTPLLSSLSATSNNSTVACINRNGSCRVKEDAFLQRYSSDPTGAVTEDNIDDAFLPVPEYVNQSVPKRPAGSVQNPVYHNQPLHPAPGRDLHYQNPHSNAVGNPEYLNTAQPTCLSSGFNSPALWIQKGSHQMSLDNPDYQQDFFPKETKPNGIFKGPTAENAEYLRVAPPSSEFIGA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 13 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
128	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
175	N-linked (GlcNAc...) asparagine	17330941	G90659AW	GlycoProtDB UniProt GlyGen
196	N-linked (GlcNAc...) asparagine		G02815KT	GlycoProtDB UniProt GlyGen
234				GlycoProtDB
352	N-linked (GlcNAc...) asparagine	16944957	G80920RR G39188ZX	GlycoProtDB UniProt GlyGen GlyConnect
413	N-linked (GlcNAc...) asparagine			UniProt GlyGen
444	N-linked (GlcNAc...) asparagine	16944957	G24193ZC	GlycoProtDB UniProt GlyGen
528	N-linked (GlcNAc...) asparagine		G43223CG	GlycoProtDB UniProt GlyGen
568	N-linked (GlcNAc...) asparagine		G27947YN	GlycoProtDB UniProt GlyGen
603	N-linked (GlcNAc...) asparagine		G27947YN	GlycoProtDB UniProt GlyGen