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Alpha-2A adrenergic receptor

Summary

UniProt ID

Q01338

Gene Symbol

Adra2a

Gene ID

11551

Organism

Mus musculus (house mouse)

External Links

PubChem: Q01338
Re-Glyco: Q01338

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Methylation
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
GABA-ergic synapse
axon terminus
presynaptic active zone membrane
postsynaptic density membrane
dopaminergic synapse
glutamatergic synapse
cytoplasm
neuronal cell body
receptor complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 26 in total

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GO Term
fear response
response to morphine
negative regulation of calcium ion-dependent exocytosis
thermoception
negative regulation of insulin secretion involved in cellular response to glucose stimulus
negative regulation of uterine smooth muscle contraction
adenylate cyclase-inhibiting adrenergic receptor signaling pathway
phospholipase C-activating adrenergic receptor signaling pathway
DNA replication
cellular response to hormone stimulus

Displaying **all 10** entries
GO Term
adrenergic receptor activity
alpha2-adrenergic receptor activity
alpha-2C adrenergic receptor binding
thioesterase binding
heterotrimeric G-protein binding
epinephrine binding
norepinephrine binding
protein kinase binding
protein homodimerization activity
protein heterodimerization activity

Annotation information from UniProt.

Sequence

MFRQEQPLAEGSFAPMGSLQPDAGNSSWNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGGQQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDACSAPPGGADRRPNGLGPERGAGPTGAEAEPLPTQLNGAPGEPAPAGPRDGDALDLEESSSSEHAERPPGPRRPDRGPRAKGKTRASQVKPGDSLPRRGPGAAGPGASGSGHGEERGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVGCPVPSQLFNFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
25	N-linked (GlcNAc...) asparagine			UniProt
29	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Adrenaline signalling through Alpha-2 adrenergic receptor	Mus musculus
Adrenaline,noradrenaline inhibits insulin secretion	Mus musculus
Adrenoceptors	Mus musculus
G alpha (i) signalling events	Mus musculus
G alpha (z) signalling events	Mus musculus
Surfactant metabolism	Mus musculus