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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Alpha-L-iduronidase
Summary
- UniProt ID
- Q01634
- Gene Symbol
-
- IDUA
- Organism
- Canis lupus familiaris (dog)
External Links
- PubChem
- Q01634
Annotation
- Keyword
-
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Glycosidase
- Lysosome
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| carbohydrate metabolic process |
| dermatan sulfate catabolic process |
| GO Term |
|---|
| lysosome |
| GO Term |
|---|
| L-iduronidase activity |
Sequence
MRPPGPRAPGLALLAALLAAPRALAEAPHLVLVDAARALRPLRPFWRSTGFCPPLPHSQADRYDLSWDQQLNLAYVGAVPHGGIEQVRTHWLLELITARESAGQGLSYNFTHLDGYLDLLRENQLLPGFELMGSPSQRFTDFEDKRQVLAWKELVSLLARRYIGRYGLSYVSKWNFETWNEPDHHDFDNVTMTLQGFLNYYDACSEGLRAASPALRFGGPGDSFHPWPRSPLCWGLLEHCHNGTNFFTGELGVRLDYISLHKKGAGSSIYILEQEQATVQQIRRLFPKFADTPVYNDEADPLVGWALPQPWRADVTYAAMVVKVVAQHQNPPRANGSAALRPALLSNDNAFLSFHPHPFTQRTLTARFQVNDTEPPHVQLLRKPVLTAMALLALLDGRQLWAEVSRGGTVLDSNHTVGVLASAHLPAGPRDAWRATVLLYASDDTRAHAARAVPVTLRLLGVPRGPGLVYVTLALDNPRCSPHGEWQRLGRPVFPTAEEFRRMRAAEDPVAEAPRPFPASGRLTLSVELRLPSLLLLHVCARPEKPPGPVTRLRALPLTRGQVLLVWSDERVGSKCLWTYEIQFSADGEVYTPISRKPSTFNLFVFSPESAVTSGSYRVRAVDYWARPGPFSTRVHYVEVPAPSGPPRPSDCERC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 109 | N-linked (GlcNAc...) asparagine |
|
||
| 189 | N-linked (GlcNAc...) asparagine |
|
||
| 242 | N-linked (GlcNAc...) asparagine |
|
||
| 335 | N-linked (GlcNAc...) asparagine |
|
||
| 371 | N-linked (GlcNAc...) asparagine |
|
||
| 414 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CS/DS degradation | Canis familiaris |
| HS-GAG degradation | Canis familiaris |
