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MIRAGE
Tyrosine-protein kinase transmembrane receptor ROR2

Summary
UniProt ID
Q01974
Gene Symbol
  • NTRKR2
  • ROR2
Gene ID
4920
Organism
Homo sapiens (human)
GlyGen
Q01974
PubChem
Q01974
The Human Metabolome Database
HMDBP01178
Re-Glyco
Q01974
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Cell membrane
  • Developmental protein
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Dwarfism
  • Glycoprotein
  • Immunoglobulin domain
  • Kringle
  • Magnesium
  • Metal-binding
  • Methylation
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Signal
  • Sulfation
  • Transmembrane helix
  • Tyrosine-protein kinase
  • Wnt signaling pathway
Gene Ontology (GO)
Displaying all 9 entries
GO Term
plasma membrane
dendrite
neuronal cell body
receptor complex
postsynapse
cell surface
microtubule
clathrin-coated endocytic vesicle membrane
glutamatergic synapse
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MARGSALPRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGYFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCDARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNAPEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 7 entries
Position Description PubMed ID GlyTouCan ID Source
70 N-linked (GlcNAc...) asparagine
152
154
157
188 N-linked (GlcNAc...) asparagine
318 N-linked (GlcNAc...) asparagine
880
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
PCP/CE pathway Homo sapiens
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Homo sapiens
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:0060764 autosomal recessive Robinow syndrome
DOID:0110969 brachydactyly type B1
DOID:674 cleft palate
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025