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Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

Summary

UniProt ID

Q02353

Gene Symbol

Ndst1
Hsst
Hsst1

Organism

Rattus norvegicus (Norway rat)

External Links

Annotation

Keyword

Direct protein sequencing
Disulfide bond
Glycoprotein
Golgi apparatus
Hydrolase
Inflammatory response
Multifunctional enzyme
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 20 in total

1

2

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GO Term
positive regulation of smoothened signaling pathway
polysaccharide biosynthetic process
cardiac septum development
inflammatory response
heart development
respiratory gaseous exchange by respiratory system
cell population proliferation
animal organ morphogenesis
glycosaminoglycan metabolic process
heparin biosynthetic process

Displaying **all 3** entries
GO Term
Golgi membrane
Golgi apparatus
trans-Golgi network membrane

Displaying **all 5** entries
GO Term
N-acetylglucosamine deacetylase activity
sulfotransferase activity
[heparan sulfate]-glucosamine N-sulfotransferase activity
deacetylase activity
heparan sulfate N-deacetylase activity

Annotation information from UniProt.

Sequence

MPALACLRRLCRHLSPQAVLFLLFVFCLFSVFVSAYYLYGWNRGLEPSADASESDCGDPPPVAPSRLLPIKPVQAVAPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRTHIPNFTFNLGYSGKFFHTGTDAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWNIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISVFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGPDASSKLRALQNRCLVPGWYATHIERWLSAFHANQILVLDGKLLRTEPAKVMDTVQKFLGVTSTVDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNTR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
231	N-linked (GlcNAc...) asparagine	UniProt
351	N-linked (GlcNAc...) asparagine	UniProt
401	N-linked (GlcNAc...) asparagine	UniProt
667	N-linked (GlcNAc...) asparagine	UniProt