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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Urokinase plasminogen activator surface receptor
Summary
- UniProt ID
- Q03405
- Gene Symbol
-
- PLAUR
- MO3
- UPAR
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell junction
- Cell membrane
- Cell projection
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| protein domain specific binding |
| urokinase plasminogen activator receptor activity |
| signaling receptor binding |
| enzyme binding |
| signaling receptor activity |
Sequence
MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 74 | N-linked (GlcNAc...) asparagine |
|
||
| 184 | N-linked (GlcNAc...) asparagine | |||
| 194 | N-linked (GlcNAc...) asparagine |
|
||
| 222 | N-linked (GlcNAc...) asparagine | |||
| 255 | N-linked (GlcNAc...) asparagine | |||
| 257 |
|
G83460ZZ
G80920RR
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Attachment of GPI anchor to uPAR | Homo sapiens |
| Dissolution of Fibrin Clot | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0040085 | bacterial sepsis | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050789 | tarsal-carpal coalition syndrome | |
| DOID:0050819 | obsolete Matthew-Wood syndrome | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:0060284 | paroxysmal nocturnal hemoglobinuria | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080348 | Alzheimer's disease 1 | |
| DOID:0110035 | Alzheimer's disease 2 |
