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Transcription factor p65

Summary

UniProt ID

Q04207

Gene Symbol

Rela
Nfkb3

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q04207
PubChem: Q04207
The O-GlcNAc Database: Q04207

Annotation

Keyword

3D-structure
Acetylation
Activator
Alternative splicing
Cytoplasm
DNA-binding
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Reference proteome
S-nitrosylation
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

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GO Term
cellular response to interleukin-6
postsynapse to nucleus signaling pathway
positive regulation of amyloid-beta formation
negative regulation of miRNA transcription
positive regulation of miRNA transcription
positive regulation of leukocyte adhesion to vascular endothelial cell
negative regulation of extrinsic apoptotic signaling pathway
liver development
hair follicle development
chromatin organization

Displaying **all 10** entries
GO Term
nucleus
protein-containing complex
synapse
glutamatergic synapse
cytosol
cytoplasm
chromatin
transcription regulator complex
NF-kappaB p50/p65 complex
NF-kappaB complex

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GO Term
sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcription coactivator binding
general transcription initiation factor binding
histone deacetylase binding
ankyrin repeat binding
DNA binding
chromatin binding
enzyme binding

Annotation information from UniProt.

Sequence

MDDLFPLIFPSEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGYYEADLCPDRSIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFHVPIEEQRGDYDLNAVRLCFQVTVRDPAGRPLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFNGPTEPRPPTRRIAVPTRNSTSVPKPAPQPYTFPASLSTINFDEFSPMLLPSGQISNQALALAPSSAPVLAQTMVPSSAMVPLAQPPAPAPVLTPGPPQSLSAPVPKSTQAGEGTLSEALLHLQFDADEDLGALLGNSTDPGVFTDLASVDNSEFQQLLNQGVSMSHSTAEPMLMEYPEAITRLVTGSQRPPDPAPTPLGTSGLPNGLSGDEDFSSIADMDFSALLSQISS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	GlyTouCan ID	Source
322	G49108TO	GlyGen The O-GlcNAc Database
370	G49108TO	GlyGen The O-GlcNAc Database
374	G49108TO	GlyGen The O-GlcNAc Database
384	G49108TO	GlyGen The O-GlcNAc Database
396	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
RIP-mediated NFkB activation via ZBP1	Mus musculus
Regulated proteolysis of p75NTR	Mus musculus
SUMOylation of immune response proteins	Mus musculus
TAK1-dependent IKK and NF-kappa-B activation	Mus musculus
TRAF6 mediated NF-kB activation	Mus musculus