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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor 1
Summary
- UniProt ID
- Q04589
- Gene Symbol
-
- Fgfr1
- Flg
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- Q04589
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Cytoplasm
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Heparin-binding
- Immunoglobulin domain
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| plasma membrane |
| cytoplasmic vesicle |
| receptor complex |
| cytosol |
| perinuclear region of cytoplasm |
| GO Term |
|---|
| SH2 domain binding |
| receptor-receptor interaction |
Sequence
MWGWRGLLFWAVLVTATLCTARPAPTLPEQAQPWGVPVEVESLLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVRDSIPADSGLYACVTNSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRRPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPSPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYDQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPNPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQDSPSFPDTRSSTCSSGEDSVFSHEPFPEEPCLPRHPTQLANGGLNRR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 77 | N-linked (GlcNAc...) asparagine |
|
||
| 117 | N-linked (GlcNAc...) asparagine |
|
||
| 227 | N-linked (GlcNAc...) asparagine |
|
||
| 240 | N-linked (GlcNAc...) asparagine |
|
||
| 264 | N-linked (GlcNAc...) asparagine |
|
||
| 296 | N-linked (GlcNAc...) asparagine |
|
||
| 317 | N-linked (GlcNAc...) asparagine |
|
||
| 330 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream signaling of activated FGFR1 | Rattus norvegicus |
| FGFR1b ligand binding and activation | Rattus norvegicus |
| FGFR1c and Klotho ligand binding and activation | Rattus norvegicus |
| FGFR1c ligand binding and activation | Rattus norvegicus |
| FRS-mediated FGFR1 signaling | Rattus norvegicus |
| Negative regulation of FGFR1 signaling | Rattus norvegicus |
| PI-3K cascade:FGFR1 | Rattus norvegicus |
| PI3K Cascade | Rattus norvegicus |
| PI3K/AKT Signaling | Rattus norvegicus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Rattus norvegicus |
