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Cyclic AMP-dependent transcription factor ATF-4

Summary

UniProt ID

Q06507

Gene Symbol

Atf4
Creb2

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q06507
PubChem: Q06507
The O-GlcNAc Database: Q06507

Annotation

Keyword

3D-structure
Acetylation
Activator
Biological rhythms
Cell membrane
Cytoskeleton
DNA-binding
Hydroxylation
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repressor
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

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GO Term
regulation of DNA-templated transcription
regulation of transcription by RNA polymerase II
transcription by RNA polymerase II
circadian rhythm
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
positive regulation of vascular endothelial growth factor production
gluconeogenesis
intracellular calcium ion homeostasis
gamma-aminobutyric acid signaling pathway

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GO Term
cytoplasm
nucleus
protein-containing complex
dendrite membrane
Lewy body core
ATF4-CREB1 transcription factor complex
ATF1-ATF4 transcription factor complex
CHOP-ATF4 complex
nuclear speck
nuclear periphery

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GO Term
DNA binding
DNA-binding transcription factor activity
RNA polymerase II cis-regulatory region sequence-specific DNA binding
general transcription initiation factor binding
cAMP response element binding protein binding
protein kinase binding
RNA polymerase II-specific DNA-binding transcription factor binding
DNA-binding transcription factor binding
promoter-specific chromatin binding
identical protein binding

Annotation information from UniProt.

Sequence

MTEMSFLNSEVLAGDLMSPFDQSGLGAEESLGLLDDYLEVAKHLKPHGFSSDKAGSSEWPAMDDGLASASDTGKEDAFSGTDWMLEKMDLKEFDFDALFRMDDLETMPDELLTTLDDTCDLFAPLVQETNKEPPQTVNPIGHLPESLIKVDQVAPFTFLQPFPCSPGVLSSTPEHSFSLELGSEVDISEGDRKPDSAAYITLIPPCVKEEDTPSDNDSGICMSPESYLGSPQHSPSTSRAPPDNLPSPGGSRGSPRPKPYDPPGVSLTAKVKTEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKARGKKRVP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites