GlyCosmos Portal

Submissions

Transforming growth factor beta-3 proprotein

Summary

UniProt ID

Q07258

Gene Symbol

Tgf-b3
Tgfb3

Gene ID

25717

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q07258
Re-Glyco: Q07258

Annotation

Keyword

Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Growth factor
Methylation
Mitogen
Reference proteome
Signal

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
secretory granule
extracellular matrix
neuronal cell body
collagen-containing extracellular matrix
cell surface
T-tubule
extracellular space

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 51 in total

1

2

3

4

5

6

Next ›

Last »
GO Term
negative regulation of transforming growth factor beta receptor signaling pathway
response to progesterone
positive regulation of collagen biosynthetic process
response to laminar fluid shear stress
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
response to estrogen
cell population proliferation
positive regulation of cell population proliferation
negative regulation of cell population proliferation

Displaying **all 9** entries
GO Term
type I transforming growth factor beta receptor binding
type III transforming growth factor beta receptor binding
identical protein binding
protein-containing complex binding
transforming growth factor beta binding
type II transforming growth factor beta receptor binding
cytokine activity
transforming growth factor beta receptor binding
growth factor activity

Annotation information from UniProt.

Sequence

MKMHLQRALVVLALLNLATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPSVMTHVPYQVLALYNSTRELLEEMHGEREEGCTQETSESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRFNVSSVEKNGTNLFRAEFRVLRVPNPSSKRTEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENVHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDSPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSSDTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
74	N-linked (GlcNAc...) asparagine	UniProt
135	N-linked (GlcNAc...) asparagine	UniProt
142	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Molecules associated with elastic fibres	Rattus norvegicus
Platelet degranulation	Rattus norvegicus
TGF-beta receptor signaling activates SMADs	Rattus norvegicus