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Transforming growth factor beta-3 proprotein

Summary

UniProt ID

Q07258

Gene Symbol

Tgfb3
Tgf-b3

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q07258

Annotation

Keyword

Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Growth factor
Methylation
Mitogen
Reference proteome
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 51 in total

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GO Term
salivary gland morphogenesis
female pregnancy
cell population proliferation
positive regulation of cell population proliferation
negative regulation of cell population proliferation
animal organ morphogenesis
gene expression
positive regulation of gene expression
mammary gland development
regulation of cell population proliferation

Displaying **all 7** entries
GO Term
cell surface
extracellular space
secretory granule
extracellular matrix
collagen-containing extracellular matrix
neuronal cell body
T-tubule

Displaying **all 9** entries
GO Term
protein-containing complex binding
identical protein binding
cytokine activity
type II transforming growth factor beta receptor binding
transforming growth factor beta receptor binding
growth factor activity
type I transforming growth factor beta receptor binding
transforming growth factor beta binding
type III transforming growth factor beta receptor binding

Annotation information from UniProt.

Sequence

MKMHLQRALVVLALLNLATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPSVMTHVPYQVLALYNSTRELLEEMHGEREEGCTQETSESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRFNVSSVEKNGTNLFRAEFRVLRVPNPSSKRTEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENVHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDSPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSSDTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
74	N-linked (GlcNAc...) asparagine	UniProt
135	N-linked (GlcNAc...) asparagine	UniProt
142	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Molecules associated with elastic fibres	Rattus norvegicus
Platelet degranulation	Rattus norvegicus
TGF-beta receptor signaling activates SMADs	Rattus norvegicus