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MIRAGE
Fibroblast growth factor receptor homolog 1
Summary
- UniProt ID
- Q07407
- Gene Symbol
-
- CG7223
- FR1
- Tk1
- htl
- Gene ID
- 42160
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- ATP-binding
- Developmental protein
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| receptor complex |
| postsynapse of neuromuscular junction |
| GO Term |
|---|
| positive regulation of glial cell migration |
| transmembrane receptor protein tyrosine kinase signaling pathway |
| heart development |
| regulation of cell shape |
| cardioblast differentiation |
Sequence
MAAAWSWRASHSTITMTSGSLVVLFLLLSIWQPAVQVEGRRQMANSQEMIKDHLGARSQNKTPAITNNANQSSTSSADLDDGAADDDDNKADLPVNVSSKPYWRNPKKMSFLQTRPSGSLLTLNCHALGNPEPNITWYRNGTVDWTRGYGSLKRNRWTLTMEDLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVNHKPILMTGPLNLTLVVNSTGSMHCKYLSDLTSKKAWIFVPCHGMTNCSNNRSIIAEDKDQLDFVNVRMEQEGWYTCVESNSLGQSNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVFGGLIFIFMTTLFVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMIMPVVRIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDIANLDTPPSTSDEEEDETDNLQKWCNY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 70 | N-linked (GlcNAc...) asparagine |
|
||
| 96 | N-linked (GlcNAc...) asparagine |
|
||
| 134 | N-linked (GlcNAc...) asparagine |
|
||
| 140 | N-linked (GlcNAc...) asparagine |
|
||
| 171 | N-linked (GlcNAc...) asparagine |
|
||
| 207 | N-linked (GlcNAc...) asparagine |
|
||
| 213 | N-linked (GlcNAc...) asparagine |
|
||
| 242 | N-linked (GlcNAc...) asparagine |
|
||
| 246 | N-linked (GlcNAc...) asparagine |
|
||
| 282 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR2b ligand binding and activation | Drosophila melanogaster |
| FGFR2c ligand binding and activation | Drosophila melanogaster |
| FGFR3b ligand binding and activation | Drosophila melanogaster |
| FGFR3c ligand binding and activation | Drosophila melanogaster |
| FGFR4 ligand binding and activation | Drosophila melanogaster |
| FRS-mediated FGFR2 signaling | Drosophila melanogaster |
| FRS-mediated FGFR3 signaling | Drosophila melanogaster |
| FRS-mediated FGFR4 signaling | Drosophila melanogaster |
| Negative regulation of FGFR2 signaling | Drosophila melanogaster |
| Negative regulation of FGFR3 signaling | Drosophila melanogaster |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3070 | high grade glioma |
