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Cystic fibrosis transmembrane conductance regulator
Summary
- UniProt ID
- Q07DZ6
- Gene Symbol
-
- CFTR
- ABCC7
- Organism
- Ornithorhynchus anatinus (platypus)
External Links
- PubChem
- Q07DZ6
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Chloride channel
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Isomerase
- Isopeptide bond
- Nucleus
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| plasma membrane |
| membrane |
| recycling endosome membrane |
| apical plasma membrane |
| early endosome membrane |
| chloride channel complex |
| cytosol |
| endoplasmic reticulum membrane |
| early endosome |
| GO Term |
|---|
| intracellularly ATP-gated chloride channel activity |
| ATP binding |
| ABC-type transporter activity |
| Sec61 translocon complex binding |
Sequence
MQRSPLERANLFSKLFFSWTKPILKKGYRQHLELSDIYQIPTADSADNLSEKLEREWDRELASKKNPKLINALRRCFFWRFMFYGLLLYLGEVTKAVQPLLLGRIIASYDPDNAHERSIAYYLGIGLCLLFIVRTLLLHPAVFGLHHIGMQMRIALFSLIYKKTLKLSSRVLDKISTGQLVSLLSNNLNKFDEGLALAHFVWIAPLQVMLLMGLLWDLLQASAFCGLAVLVVLVLFQAWLGHRMMKYRDRRAGKINERLVITAEIIENIQSVKAYCWEEAMENMIESLRETELKLTRKAAYMRYFNSSAFFFSGFFVVFLSVLPSMLTKGIVLRKIFTTISFCIVLRMAVTRQFPWAVQMWYDSIGAIYKIQDFLQKEEYKTLEYNLTTTDVVMENVTAFWDEGFGELLVKAKQNDSSRKVSSDDKNLIFSNISLLGPPVLKDISFKIEKGQLLAVAGSTGAGKTSLLMMIMGELEPLEGKIKHSGRISFSPQFSWIMPGTIKENIVFGVSFDEYRYRSVIKACQLEEEISKFAEKDNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSCYFYGAFSELQNLRPDFSSKLMGYDSFDQFSAERRNSILTETLRRFSLDGDAAGSWNETKKQSFKQTGEFGERRKNSILNPLNSIRKFSLVQKAPLQMNCIDETLDEPPERKLSLVPDSEPGEAILPRSNMLNPGPVLRARRRQSVLNLMTRPSIHQGSSLYKKGSASARKMSVAPQSNMSEMDIYSRRLSKDSGLEISEEINEEDLKECFIDDIESTTSVTTWNTYLRYMTIHKKLIFVLMMCLVIFLIEVAASLVGLCLFKDGASRMNSTSNLNHTSTLDWFAVIVTNTSTYYMFYIYVGVADTLLALGFLRGLPLVHSLISVSKILHQKMLHSVLQAPMSTFNTLKTGSILNRFSKDMAILDDLLPLTIFDFIQLLLIVIGAVTVVSALQPYIFLASVPVVIAFVLLRAYFLRTSQQLKQLESEARSPIFTHLITSLKGLWTLRAFGRQTYFEALFHKALNLHTANWFLYLSTLRWFQMRIEMVFVIFFILVTFISILTTGDGEGKVGIVLTLAMNIMGTLQWAVNASIDVDSLMRSVSRVFKFIDMPTEEHRPTHPAKNKDISGVLIIENQHVKREKNWPSGGQMTVQDLTAKYLDGGPAILDNISFSISSGQRVGLLGRTGSGKSTLLFAFLRLLNTEGDIRIDGISWDAVPVQQWRKAFGVIPQKVFIFSGSFRKNLDPYGQWTDQELWKVAEEVGLKSVIEQFPGQLDFVLIDGGYVLSHGHRQLMCLARSVLSKAKILLLDEPSAHLDPITYQVIRKTLKQAFTNCTVILSEHRIEAMLECQRFLVIEENKVRQYESIQKLLNEKSVFKQAISHSDKMKLFPIHRRNSSKRLSRPKITALQEETEEEVQDTRL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
