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Runt-related transcription factor 2

Summary

UniProt ID

Q08775

Gene Symbol

Aml3
Cbfa1
Osf2
Pebp2a
Runx2

Gene ID

12393

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q08775
PubChem: Q08775
O-GlcNAcAtlas: Q08775
Re-Glyco: Q08775

Annotation

Keyword

Alternative splicing
Cytoplasm
DNA-binding
Differentiation
Direct protein sequencing
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
chromatin
nucleus
cytoplasm
protein-containing complex
nucleoplasm
cytosol
transcription regulator complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 39 in total

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GO Term
positive regulation of osteoblast differentiation
negative regulation of smoothened signaling pathway
SMAD protein signal transduction
gene expression
skeletal system development
endochondral ossification
cell population proliferation
positive regulation of cell population proliferation
regulation of gene expression
positive regulation of gene expression

Displaying entries **1 - 10** of 11 in total

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GO Term
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
ATP binding
protein domain specific binding
chromatin DNA binding
bHLH transcription factor binding
DNA-binding transcription factor binding
transcription cis-regulatory region binding
cis-regulatory region sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MLHSPHKQPQNHKCGANFLQEDCKKALAFKWLISAGHYQPPRPTESVSALTTVHAGIFKAASSIYNRGHKFYLEKKGGTMASNSLFSAVTPCQQSFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSSLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSASYQFPMVPGGDRSPSRMVPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites