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Adenylate cyclase type 1
Summary
- UniProt ID
- Q08828
- Gene Symbol
-
- ADCY1
- Gene ID
- 107
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q08828
- The Human Metabolome Database
- HMDBP00711
- Re-Glyco
- Q08828
Annotation
- Keyword
-
- ATP-binding
- Biological rhythms
- Calmodulin-binding
- Cell membrane
- Cytoplasm
- Glycoprotein
- Lyase
- Magnesium
- Manganese
- Metal-binding
- Non-syndromic deafness
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- cAMP biosynthesis
- Gene Ontology (GO)
| GO Term |
|---|
| metal ion binding |
| calcium- and calmodulin-responsive adenylate cyclase activity |
| adenylate cyclase activity |
| calmodulin binding |
| ATP binding |
Sequence
MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQKYHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVVVLLLLVFCICFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNSSLVVLSSGGQRTALPTLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYILVLELSGYTRTGGGAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQIRSLGLDRKMCPFGRAGLQGRRPPVCPMPGVSVRAGLPPHSPGQYLPSAAAGKEA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 704 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ADORA2B mediated anti-inflammatory cytokines production | Homo sapiens |
| Adenylate cyclase activating pathway | Homo sapiens |
| Adenylate cyclase inhibitory pathway | Homo sapiens |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | Homo sapiens |
| FCGR3A-mediated IL10 synthesis | Homo sapiens |
| G alpha (i) signalling events | Homo sapiens |
| G alpha (s) signalling events | Homo sapiens |
| G alpha (z) signalling events | Homo sapiens |
| GPER1 signaling | Homo sapiens |
| Glucagon signaling in metabolic regulation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110501 | autosomal recessive nonsyndromic deafness 44 |
