Fibroblast growth factor receptor homolog 2

Summary
UniProt ID
Q09147
Gene Symbol
  • btl
  • FR2
  • HD-311
  • Tk2
Organism
Drosophila melanogaster (fruit fly)
PubChem
Q09147
Annotation
Keyword
  • ATP-binding
  • Developmental protein
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
Gene Ontology (GO)
Sequence
MAKVPITLVMIIAIVSAAADLGCDYGHHRCYIDVTVENSPRQRHLLSDMDITLQCVRPMAKWFYEDKFQLRATLLRLERAQSGNSGNYGCLDSQNRWYNISLVVGHKEPVGNDIASFVKLEDAPALPESDLFFQPLNESRSLKLLQPLPKTVQRTAGGLFQLNCSPMDPDAKGVNISWLHNDTQILGGRGRIKLKRWSLTVGQLQPEDAGSYHCELCVEQDCQRSNPTQLEVISRKHTVPMLKPGYPRNTSIALGDNVSIECLLEDSALEPKITWLHKGNADNIDDLLQRLREQSQLPVDVTRLITRMDEPQVLRLGNVLMEDGGWYICIAENQVGRTVAASYVDLYSPSDTTTVRTTTTTTVASPIPTASTGEDNDDDVENPAAEASGGVGPPVFRKELKRLQHSLSGNTVNLACPVYGKANITWTKDKKPLNRELGVYVQKNWTLRFVEATSEDSGLYNCKVCNAWGCIQFDFSVQINDRTRSAPIIVVPQNQTVKVNGSLVMKCTVYSDLHPTVSWKRVVLKNASLDGLKSVEIQNLNFTVTNDSVVLTLRNVTFDQEGWYTCLASSGLGRSNSSVYLRVVSPLPPLEIYALLHAHPLGFTLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIETVHQWTKKVIIYRPGGEEGSGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSNPNDAYLDLSMPMLETPPSSGDEDDGSDTETFRETSPLRYQYTYKFN
Glycosylation Sites
Displaying entries 11 - 15 of 15 in total
Position Description PubMed ID GlyTouCan ID Source
526 N-linked (GlcNAc...) asparagine
541 N-linked (GlcNAc...) asparagine
546 N-linked (GlcNAc...) asparagine
555 N-linked (GlcNAc...) asparagine
576 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 11 - 20 of 34 in total
Pathway Name Organism
FRS-mediated FGFR2 signaling Drosophila melanogaster
FRS-mediated FGFR3 signaling Drosophila melanogaster
FRS-mediated FGFR4 signaling Drosophila melanogaster
Negative regulation of FGFR1 signaling Drosophila melanogaster
Negative regulation of FGFR2 signaling Drosophila melanogaster
Negative regulation of FGFR3 signaling Drosophila melanogaster
Negative regulation of FGFR4 signaling Drosophila melanogaster
PI-3K cascade:FGFR1 Drosophila melanogaster
PI-3K cascade:FGFR2 Drosophila melanogaster
PI-3K cascade:FGFR3 Drosophila melanogaster

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024