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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
Summary
- UniProt ID
- Q09328
- Gene Symbol
-
- MGAT5
- GGNT5
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011814
- GlyGen
- Q09328
- PubChem
- Q09328
- The Human Metabolome Database
- HMDBP01705
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Reference proteome
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| Golgi apparatus |
| membrane |
| extracellular exosome |
| GO Term |
|---|
| alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity |
| manganese ion binding |
| protein phosphatase inhibitor activity |
Sequence
MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYDLKKTLAVLLDNILQRIGKLESKVDNLVVNGTGTNSTNSTTAVPSLVALEKINVADIINGAQEKCVLPPMDGYPHCEGKIKWMKDMWRSDPCYADYGVDGSTCSFFIYLSEVENWCPHLPWRAKNPYEEADHNSLAEIRTDFNILYSMMKKHEEFRWMRLRIRRMADAWIQAIKSLAEKQNLEKRKRKKVLVHLGLLTKESGFKIAETAFSGGPLGELVQWSDLITSLYLLGHDIRISASLAELKEIMKKVVGNRSGCPTVGDRIVELIYIDIVGLAQFKKTLGPSWVHYQCMLRVLDSFGTEPEFNHANYAQSKGHKTPWGKWNLNPQQFYTMFPHTPDNSFLGFVVEQHLNSSDIHHINEIKRQNQSLVYGKVDSFWKNKKIYLDIIHTYMEVHATVYGSSTKNIPSYVKNHGILSGRDLQFLLRETKLFVGLGFPYEGPAPLEAIANGCAFLNPKFNPPKSSKNTDFFIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNNQEEVEDAVKAILNQKIEPYMPYEFTCEGMLQRINAFIEKQDFCHGQVMWPPLSALQVKLAEPGQSCKQVCQESQLICEPSFFQHLNKDKDMLKYKVTCQSSELAKDILVPSFDPKNKHCVFQGDLLLFSCAGAHPRHQRVCPCRDFIKGQVALCKDCL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 33 |
|
|||
| 38 |
|
|||
| 110 | N-linked (GlcNAc...) asparagine | |||
| 115 | N-linked (GlcNAc...) asparagine |
|
||
| 118 | N-linked (GlcNAc...) asparagine |
|
||
| 121 |
|
|||
| 334 | N-linked (GlcNAc...) asparagine |
|
||
| 433 | N-linked (GlcNAc...) asparagine |
|
||
| 447 | N-linked (GlcNAc...) asparagine |
G57321FI
G94971OC
G43417UB
G83460ZZ
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Maturation of spike protein | Homo sapiens |
| N-Glycan antennae elongation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110758 | type 1 diabetes mellitus 21 | |
| DOID:0110759 | type 1 diabetes mellitus 22 | |
| DOID:0110760 | type 1 diabetes mellitus 23 | |
| DOID:0110761 | type 1 diabetes mellitus 24 | |
| DOID:0110892 | inflammatory bowel disease 1 | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:1040 | chronic lymphocytic leukemia | |
| DOID:10534 | stomach cancer | |
| DOID:11054 | urinary bladder cancer |
