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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glypican-1
Summary
- UniProt ID
- Q0V9W0
- Gene Symbol
-
- gpc1
- Organism
- Xenopus tropicalis (tropical clawed frog)
External Links
- PubChem
- Q0V9W0
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- GPI-anchor
- Heparan sulfate
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of protein localization to membrane |
| negative regulation of fibroblast growth factor receptor signaling pathway |
| cell migration |
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| synapse |
| collagen-containing extracellular matrix |
| cell surface |
| side of membrane |
| GO Term |
|---|
| fibroblast growth factor binding |
Sequence
MERLCWGWWWHLGILCLMHWAAGDTGSKTKSCSEVKQVYLAKGFSLNGAPQSEISGEHLRICPQGYTCCTSEMEENFANISRVEFEAKLRESSASIQRLLTTQHRNFDSYFQDLLNTSERVLQERFPSQYGDLYSQNSKIFRDLYSELRQYYRGSGINLEEALIEFWSRLLERVFKAQHTQYSFSEEYMDCLVKQYEQLKPFGDTPREVKLKAARAFIAARSFVQGLNAAADVVRKANQVPMSTECARAVMKLVYCPHCRGHSSIKLCSNYCWNVMRGCLANQADLDSEWRNLIESLLLVADKFNGASNVENIVGAIHTKISEAITHMQENKELLTNKVFKICGTPKKTNKGSKSEERRRKGKATQEDKSAVATMDNLISDVKGILSDIQDYWVSLPSLFCTEKVTAGPGNEDKCWNGITKGRYMPEPMGSGLANQINNPEVDVDITKPDMTIRQQIMQLKIMTSRLRNAYNGNDVDFQDTSDDMSGSGSGDGCNEDLCGSGRKLSRETVIIQPATHAVPRQPNPGETGKGTRLSSWDLLICLVALLVAQCTRW
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 79 | N-linked (GlcNAc...) asparagine |
|
||
| 116 | N-linked (GlcNAc...) asparagine |
|
||
| 486 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 488 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 490 | O-linked (Xyl...) (heparan sulfate) serine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Xenopus tropicalis |
| Cell surface interactions at the vascular wall | Xenopus tropicalis |
| HS-GAG biosynthesis | Xenopus tropicalis |
| HS-GAG degradation | Xenopus tropicalis |
