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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Galactoside alpha-(1,2)-fucosyltransferase 2
Summary
- UniProt ID
- Q10981
- Gene Symbol
-
- FUT2
- SEC2
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q10981
- The Human Metabolome Database
- HMDBP00466
Annotation
- Keyword
-
- Blood group antigen
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Lipid metabolism
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| Golgi apparatus |
| extracellular exosome |
| Golgi cisterna membrane |
| GO Term |
|---|
| galactoside 2-alpha-L-fucosyltransferase activity |
| fucosyltransferase activity |
| alpha-(1,2)-fucosyltransferase activity |
Sequence
MLVVQMPFSFPMAHFILFVFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVNGSRPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFVVTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLSPLLKH
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ABO blood group biosynthesis | Homo sapiens |
| Glycosphingolipid biosynthesis | Homo sapiens |
| Lewis blood group biosynthesis | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0060025 | immunoglobulin alpha deficiency | |
| DOID:0060180 | colitis | |
| DOID:0060188 | jejunoileitis | |
| DOID:0060189 | ileitis | |
| DOID:0060190 | ileocolitis | |
| DOID:0060191 | gastroduodenal Crohn's disease | |
| DOID:0060192 | Crohn's colitis | |
| DOID:0060262 | gallbladder disease | |
| DOID:0060643 | primary sclerosing cholangitis |
