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MIRAGE
Glutamate receptor ionotropic, kainate 2

Summary
UniProt ID
Q13002
Gene Symbol
  • GLUR6
  • GRIK2
Gene ID
2898
Organism
Homo sapiens (human)
GlyGen
Q13002
PubChem
Q13002
The Human Metabolome Database
HMDBP01813
Re-Glyco
Q13002
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Disease variant
  • Disulfide bond
  • Epilepsy
  • Glycoprotein
  • Intellectual disability
  • Isopeptide bond
  • Ligand-gated ion channel
  • Phosphoprotein
  • Postsynaptic cell membrane
  • RNA editing
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Ubl conjugation
Gene Ontology (GO)
Displaying all 8 entries
GO Term
kainate selective glutamate receptor complex
hippocampal mossy fiber to CA3 synapse
glutamatergic synapse
plasma membrane
neuronal cell body
presynaptic membrane
postsynaptic density membrane
mossy fiber rosette
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRRLPGKETMA
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 9 entries
Position Description PubMed ID GlyTouCan ID Source
67 N-linked (GlcNAc...) asparagine
73 N-linked (GlcNAc...) asparagine
275 N-linked (GlcNAc...) asparagine
378 N-linked (GlcNAc...) asparagine
412 N-linked (GlcNAc...) asparagine
423 N-linked (GlcNAc...) asparagine
430 N-linked (GlcNAc...) asparagine
546 N-linked (GlcNAc...) asparagine
751 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Activation of Ca-permeable Kainate Receptor Homo sapiens
Activation of Na-permeable kainate receptors Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:0081182 autosomal recessive intellectual developmental disorder 6
DOID:12858 Huntington's disease
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025