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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Chitotriosidase-1
Summary
- UniProt ID
- Q13231
- Gene Symbol
-
- CHIT1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q13231
- PubChem
- Q13231
- The Human Metabolome Database
- HMDBP01031
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Chitin degradation
- Chitin-binding
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Glycosidase
- Lysosome
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| polysaccharide catabolic process |
| immune response |
| response to bacterium |
| polysaccharide digestion |
| chitin catabolic process |
| GO Term |
|---|
| specific granule lumen |
| tertiary granule lumen |
| extracellular region |
| extracellular space |
| lysosome |
| GO Term |
|---|
| hydrolase activity, hydrolyzing O-glycosyl compounds |
| chitinase activity |
| chitin binding |
| endochitinase activity |
Sequence
MVRSVAWAGFMVLLMIPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTWN
Glycosylation Sites
G43417UB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Digestion of dietary carbohydrate | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14504 | Niemann-Pick disease | |
| DOID:14525 | Reye syndrome | |
| DOID:1485 | cystic fibrosis | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1837 | diabetic ketoacidosis | |
| DOID:1883 | hepatitis C | |
| DOID:1926 | Gaucher's disease | |
| DOID:1927 | sphingolipidosis | |
| DOID:1936 | atherosclerosis |
