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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Phospholipase D1
Summary
- UniProt ID
- Q13393
- Gene Symbol
-
- PLD1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q13393
- PubChem
- Q13393
- SwissLipids
- The Human Metabolome Database
- HMDBP00082
- The O-GlcNAc Database
- Q13393
- RaftProt
- Q13393
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasm
- Disease variant
- Endoplasmic reticulum
- Endosome
- Golgi apparatus
- Hydrolase
- Lipid degradation
- Membrane
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi apparatus |
| plasma membrane |
| membrane |
| endocytic vesicle |
| intracellular membrane-bounded organelle |
| GO Term |
|---|
| phospholipase D activity |
| phosphatidylinositol binding |
| N-acylphosphatidylethanolamine-specific phospholipase D activity |
Sequence
MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSAIYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNCCGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKGYFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGLKPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 10 |
|
|||
| 629 |
|
|||
| 632 |
|
|||
| 641 |
|
G80920RR
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CDC42 GTPase cycle | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| RAC1 GTPase cycle | Homo sapiens |
| RHOA GTPase cycle | Homo sapiens |
| RHOG GTPase cycle | Homo sapiens |
| Role of phospholipids in phagocytosis | Homo sapiens |
| Synthesis of PA | Homo sapiens |
| Synthesis of PG | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:5077 | subependymal giant cell astrocytoma | |
| DOID:5517 | stomach carcinoma | |
| DOID:552 | pneumonia | |
| DOID:5644 | tricuspid valve prolapse | |
| DOID:5672 | large intestine cancer | |
| DOID:5844 | myocardial infarction | |
| DOID:5854 | silent myocardial infarction | |
| DOID:6000 | congestive heart failure | |
| DOID:612 | primary immunodeficiency disease | |
| DOID:6367 | acral lentiginous melanoma |
