Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Phospholipase D1
Summary
- UniProt ID
- Q13393
- Gene Symbol
-
- PLD1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q13393
- PubChem
- Q13393
- SwissLipids
- The Human Metabolome Database
- HMDBP00082
- The O-GlcNAc Database
- Q13393
- RaftProt
- Q13393
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasm
- Disease variant
- Endoplasmic reticulum
- Endosome
- Golgi apparatus
- Hydrolase
- Lipid degradation
- Membrane
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Gene Ontology (GO)
| GO Term |
|---|
| tertiary granule membrane |
| cholinergic synapse |
| apical plasma membrane |
| late endosome membrane |
| endosome |
| endoplasmic reticulum membrane |
| specific granule membrane |
| perinuclear region of cytoplasm |
| Golgi membrane |
| lysosomal membrane |
| GO Term |
|---|
| phospholipase D activity |
| phosphatidylinositol binding |
| N-acylphosphatidylethanolamine-specific phospholipase D activity |
Sequence
MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSAIYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNCCGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKGYFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGLKPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 10 |
|
|||
| 629 |
|
|||
| 632 |
|
|||
| 641 |
|
G80920RR
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CDC42 GTPase cycle | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| RAC1 GTPase cycle | Homo sapiens |
| RHOA GTPase cycle | Homo sapiens |
| RHOG GTPase cycle | Homo sapiens |
| Role of phospholipids in phagocytosis | Homo sapiens |
| Synthesis of PA | Homo sapiens |
| Synthesis of PG | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease | |
| DOID:10914 | amnestic disorder | |
| DOID:11111 | hydronephrosis | |
| DOID:11247 | disseminated intravascular coagulation | |
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:11502 | mitral valve insufficiency | |
| DOID:11832 | visual epilepsy | |
| DOID:11847 | coronary thrombosis | |
| DOID:11870 | Pick's disease | |
| DOID:12382 | complex partial epilepsy |
