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Interleukin-18 receptor 1

Summary

UniProt ID

Q13478

Gene Symbol

IL18R1
IL1RRP

Organism

Homo sapiens (human)

External Links

GlyGen: Q13478
PubChem: Q13478
The Human Metabolome Database: HMDBP12400

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Glycoprotein
Hydrolase
Immunoglobulin domain
Inflammatory response
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

1

2

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GO Term
positive regulation of non-canonical NF-kappaB signal transduction
natural killer cell activation
inflammatory response
immune response
signal transduction
positive regulation of type II interferon production
interleukin-18-mediated signaling pathway
T-helper 1 cell differentiation
positive regulation of NF-kappaB transcription factor activity
positive regulation of T-helper 1 cell cytokine production

Displaying **all 2** entries
GO Term
plasma membrane
interleukin-18 receptor complex

Displaying **all 6** entries
GO Term
interleukin-1 receptor activity
signaling receptor activity
NAD+ nucleosidase activity
interleukin-18 binding
interleukin-18 receptor activity
NAD+ nucleotidase, cyclic ADP-ribose generating

Annotation information from UniProt.

Sequence

MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCFTERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSES

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
40			G57321FI	GlyGen
91	N-linked (GlcNAc...) asparagine	25500532		UniProt GlyGen
102	N-linked (GlcNAc...) asparagine	25500532		UniProt GlyGen
150	N-linked (GlcNAc...) asparagine	25500532		UniProt GlyGen
197	N-linked (GlcNAc...) asparagine	25261253 25500532	G80920RR	UniProt GlyGen
203	N-linked (GlcNAc...) asparagine	25261253 25500532	G80920RR	UniProt GlyGen
236	N-linked (GlcNAc...) asparagine	25261253 25500532		UniProt GlyGen
255	N-linked (GlcNAc...) asparagine			UniProt GlyGen
297	N-linked (GlcNAc...) asparagine	25261253 25500532		UniProt GlyGen