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Transforming growth factor beta activator LRRC32

Summary

UniProt ID

Q14392

Gene Symbol

LRRC32
D11S833E

Organism

Homo sapiens (human)

External Links

GlyGen: Q14392
PubChem: Q14392
The Human Metabolome Database: HMDBP14558
The O-GlcNAc Database: Q14392
RaftProt: Q14392

Annotation

Keyword

3D-structure
Cell membrane
Disease variant
Disulfide bond
Glycoprotein
Growth factor binding
Intellectual disability
Leucine-rich repeat
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
negative regulation of cytokine production
positive regulation of gene expression
secondary palate development
negative regulation of activated T cell proliferation
transforming growth factor beta receptor signaling pathway
regulation of transforming growth factor beta activation
regulation of transforming growth factor beta3 activation

Displaying **all 6** entries
GO Term
extracellular space
plasma membrane
extracellular matrix
nucleoplasm
external side of plasma membrane
cell surface

Displaying 1 entry
GO Term
transforming growth factor beta binding

Annotation information from UniProt.

Sequence

MRPQILLLLALLTLGLAAQHQDKVPCKMVDKKVSCQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFSSQEEVSLSHVRPEDCEKGGLKNINLIIILTFILVSAILLTTLAACCCVRRQKFNQQYKA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
203	N-linked (GlcNAc...) asparagine		G99668VU G80479JV G26330YA G83460ZZ G46503DX G80920RR G62765YT	UniProt GlyGen
271	N-linked (GlcNAc...) asparagine		G83460ZZ G80920RR	UniProt GlyGen
308	N-linked (GlcNAc...) asparagine	19159218		UniProt GlyGen
345	N-linked (GlcNAc...) asparagine			UniProt GlyGen
371			G49108TO	GlyGen The O-GlcNAc Database
377			G49108TO	GlyGen The O-GlcNAc Database
545	N-linked (GlcNAc...) asparagine			UniProt GlyGen