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Metabotropic glutamate receptor 2

Summary

UniProt ID

Q14416

Gene Symbol

GRM2
GPRC1B
MGLUR2

Organism

Homo sapiens (human)

External Links

PubChem: Q14416

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Signal
Synapse
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 15 in total

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GO Term
regulation of synaptic transmission, glutamatergic
presynaptic modulation of chemical synaptic transmission
G protein-coupled glutamate receptor signaling pathway
behavioral response to nicotine
long-term synaptic depression
regulation of response to drug
response to cocaine
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
negative regulation of adenylate cyclase activity
intracellular glutamate homeostasis

Displaying **all 6** entries
GO Term
plasma membrane
axon
dendrite
presynaptic membrane
glutamatergic synapse
astrocyte projection

Displaying **all 5** entries
GO Term
G protein-coupled receptor activity
group II metabotropic glutamate receptor activity
calcium channel regulator activity
glutamate receptor activity
scaffold protein binding

Annotation information from UniProt.

Sequence

MGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
203	N-linked (GlcNAc...) asparagine	UniProt
286	N-linked (GlcNAc...) asparagine	UniProt
338	N-linked (GlcNAc...) asparagine	UniProt
402	N-linked (GlcNAc...) asparagine	UniProt
547	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Class C/3 (Metabotropic glutamate/pheromone receptors)	Homo sapiens
G alpha (i) signalling events	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements