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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Polypeptide N-acetylgalactosaminyltransferase 3
Summary
- UniProt ID
- Q14435
- Gene Symbol
-
- GALNT3
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- Q14435
- PubChem
- Q14435
- The Human Metabolome Database
- HMDBP00995
Annotation
- Keyword
-
- Alternative splicing
- Disease variant
- Disulfide bond
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Lectin
- Manganese
- Metal-binding
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| Golgi apparatus |
| Golgi cisterna membrane |
| perinuclear region of cytoplasm |
| membrane |
| extracellular exosome |
| GO Term |
|---|
| polypeptide N-acetylgalactosaminyltransferase activity |
| calcium ion binding |
| manganese ion binding |
| carbohydrate binding |
Sequence
MAHLKRLVKLHIKRHYHKKFWKLGAVIFFFIIVLVLMQREVSVQYSKEESRMERNMKNKNKMLDLMLEAVNNIKDAMPKMQIGAPVRQNIDAGERPCLQGYYTAAELKPVLDRPPQDSNAPGASGKAFKTTNLSVEEQKEKERGEAKHCFNAFASDRISLHRDLGPDTRPPECIEQKFKRCPPLPTTSVIIVFHNEAWSTLLRTVHSVLYSSPAILLKEIILVDDASVDEYLHDKLDEYVKQFSIVKIVRQRERKGLITARLLGATVATAETLTFLDAHCECFYGWLEPLLARIAENYTAVVSPDIASIDLNTFEFNKPSPYGSNHNRGNFDWSLSFGWESLPDHEKQRRKDETYPIKTPTFAGGLFSISKEYFEYIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIMPCSVVGHVFRSKSPHSFPKGTQVIARNQVRLAEVWMDEYKEIFYRRNTDAAKIVKQKAFGDLSKRFEIKHRLQCKNFTWYLNNIYPEVYVPDLNPVISGYIKSVGQPLCLDVGENNQGGKPLIMYTCHGLGGNQYFEYSAQHEIRHNIQKELCLHAAQGLVQLKACTYKGHKTVVTGEQIWEIQKDQLLYNPFLKMCLSANGEHPSLVSCNPSDPLQKWILSQND
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 127 |
|
|||
| 130 |
|
|||
| 131 |
|
|||
| 132 | N-linked (GlcNAc...) asparagine | |||
| 297 | N-linked (GlcNAc...) asparagine |
|
||
| 484 | N-linked (GlcNAc...) asparagine |
|
G57321FI
G24084IV
G83229XP
G75983OB
G62765YT
G95177YH
G23719VF
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective GALNT3 causes HFTC | Homo sapiens |
| FGFR3c ligand binding and activation | Homo sapiens |
| O-linked glycosylation of mucins | Homo sapiens |
Human Protein Atlas