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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Transcription factor HES-1
Summary
- UniProt ID
- Q14469
- Gene Symbol
-
- HES1
- BHLHB39
- HL
- HRY
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- DNA-binding
- Nucleus
- Reference proteome
- Repressor
- Transcription regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cellular response to interleukin-1 |
| negative regulation of calcium ion import |
| response to thyroid hormone |
| neuronal stem cell population maintenance |
| GO Term |
|---|
| chromatin |
| nucleus |
| cytoplasm |
| nuclear matrix |
| nucleoplasm |
| GO Term |
|---|
| transcription corepressor binding |
| JUN kinase binding |
| histone deacetylase binding |
| E-box binding |
| N-box binding |
Sequence
MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQPHPALQAPPPPPPGPGGPQHAPFAPPPPLVPIPGGAAPPPGGAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSLTADSMWRPWRN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 55 |
|
|||
| 84 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | Homo sapiens |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | Homo sapiens |
| NOTCH1 Intracellular Domain Regulates Transcription | Homo sapiens |
| NOTCH2 intracellular domain regulates transcription | Homo sapiens |
| NOTCH3 Intracellular Domain Regulates Transcription | Homo sapiens |
| NOTCH4 Intracellular Domain Regulates Transcription | Homo sapiens |
| RUNX2 regulates osteoblast differentiation | Homo sapiens |
| RUNX3 regulates NOTCH signaling | Homo sapiens |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | Homo sapiens |
