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Semaphorin-3A
Summary
- UniProt ID
- Q14563
- Gene Symbol
-
- SEMA3A
- SEMAD
- Gene ID
- 10371
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Developmental protein
- Differentiation
- Disease variant
- Disulfide bond
- Glycoprotein
- Hypogonadotropic hypogonadism
- Immunoglobulin domain
- Kallmann syndrome
- Neurogenesis
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| axon |
| dendrite |
| glutamatergic synapse |
| extracellular region |
| extracellular space |
| GO Term |
|---|
| semaphorin receptor binding |
| chemorepellent activity |
| neuropilin binding |
Sequence
MGWLTRIVCLFWGVLLTARANYQNGKNNVPRLKLSYKEMLESNNVITFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFDLVNIKDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKAYNQTHLYACGTGAFHPICTYIEIGHHPEDNIFKLENSHFENGRGKSPYDPKLLTASLLIDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPKFISAHLISESDNPEDDKVYFFFRENAIDGEHSGKATHARIGQICKNDFGGHRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNFKDPKNPVVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGPYAHRDGPNYQWVPYQGRVPYPRPGTCPSKTFGGFDSTKDLPDDVITFARSHPAMYNPVFPMNNRPIVIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSIPKETWYDLEEVLLEEMTVFREPTAISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAECCLARDPYCAWDGSACSRYFPTAKRRTRRQDIRNGDPLTHCSDLHHDNHHGHSPEERIIYGVENSSTFLECSPKSQRALVYWQFQRRNEERKEEIRVDDHIIRTDQGLLLRSLQQKDSGNYLCHAVEHGFIQTLLKVTLEVIDTEHLEELLHKDDDGDGSKTKEMSNSMTPSQKVWYRDFMQLINHPNLNTMDEFCEQVWKRDRKQRRQRPGHTPGNSNKWKHLQENKKGRNRRTHEFERAPRSV
Glycosylation Sites
G49108TO
G70994MS
G80920RR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CRMPs in Sema3A signaling | Homo sapiens |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | Homo sapiens |
| Sema3A PAK dependent Axon repulsion | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0090080 | hypogonadotropic hypogonadism 16 with or without anosmia |
