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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Indian hedgehog protein
Summary
- UniProt ID
- Q14623
- Gene Symbol
-
- IHH
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011903
- GlyGen
- Q14623
- PubChem
- Q14623
Annotation
- Keyword
-
- 3D-structure
- Autocatalytic cleavage
- Calcium
- Cell membrane
- Developmental protein
- Disease variant
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Metal-binding
- Palmitate
- Protease
- Reference proteome
- Secreted
- Signal
- Transferase
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of apoptotic process |
| GO Term |
|---|
| endoplasmic reticulum membrane |
| Golgi membrane |
| extracellular space |
| plasma membrane |
| extracellular matrix |
| GO Term |
|---|
| calcium ion binding |
| peptidase activity |
| patched binding |
| cholesterol-protein transferase activity |
Sequence
MSPARLRPRLHFCLVLLLLLVVPAAWGCGPGRVVGSRRRPPRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAAAKTGGCFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGSPTFSDVLIFLDREPHRLRAFQVIETQDPPRRLALTPAHLLFTADNHTEPAARFRATFASHVQPGQYVLVAGVPGLQPARVAAVSTHVALGAYAPLTKHGTLVVEDVVASCFAAVADHHLAQLAFWPLRLFHSLAWGSWTPGEGVHWYPQLLYRLGRLLLEEGSFHPLGMSGAGS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 282 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of SMO | Homo sapiens |
| Class B/2 (Secretin family receptors) | Homo sapiens |
| Formation of lateral plate mesoderm | Homo sapiens |
| HHAT G278V doesn't palmitoylate Hh-Np | Homo sapiens |
| Hedgehog 'on' state | Homo sapiens |
| Hedgehog ligand biogenesis | Homo sapiens |
| Ligand-receptor interactions | Homo sapiens |
| RUNX2 regulates chondrocyte maturation | Homo sapiens |
| Release of Hh-Np from the secreting cell | Homo sapiens |
