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Ubiquitin carboxyl-terminal hydrolase 10

Summary

UniProt ID

Q14694

Gene Symbol

USP10
KIAA0190

Organism

Homo sapiens (human)

External Links

GlyGen: Q14694
PubChem: Q14694
The Human Metabolome Database: HMDBP10135
The O-GlcNAc Database: Q14694
O-GlcNAcAtlas: Q14694

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Autophagy
Cytoplasm
DNA repair
Endosome
Nucleus
Phosphoprotein
Reference proteome
Thiol protease
Ubl conjugation
Ubl conjugation pathway

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

1

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GO Term
proteolysis
autophagy
regulation of autophagy
translesion synthesis
DNA damage response
negative regulation of canonical NF-kappaB signal transduction
protein deubiquitination
DNA damage response, signal transduction by p53 class mediator
monoubiquitinated protein deubiquitination
negative regulation of stress granule assembly

Displaying **all 8** entries
GO Term
cytosol
cytosolic ribosome
nucleoplasm
early endosome
nucleus
cytoplasm
protein-containing complex
intermediate filament cytoskeleton

Displaying **all 6** entries
GO Term
transmembrane transporter binding
molecular function inhibitor activity
p53 binding
cysteine-type endopeptidase activity
cysteine-type deubiquitinase activity
RNA binding

Annotation information from UniProt.

Sequence

MALHSPQYIFGDFSPDEFNQFFVTPRSSVELPPYSGTVLCGTQAVDKLPDGQEYQRIEFGVDEVIEPSDTLPRTPSYSISSTLNPQAPEFILGCTASKITPDGITKEASYGSIDCQYPGSALALDGSSNVEAEVLENDGVSGGLGQRERKKKKKRPPGYYSYLKDGGDDSISTEALVNGHANSAVPNSVSAEDAEFMGDMPPSVTPRTCNSPQNSTDSVSDIVPDSPFPGALGSDTRTAGQPEGGPGADFGQSCFPAEAGRDTLSRTAGAQPCVGTDTTENLGVANGQILESSGEGTATNGVELHTTESIDLDPTKPESASPPADGTGSASGTLPVSQPKSWASLFHDSKPSSSSPVAYVETKYSPPAISPLVSEKQVEVKEGLVPVSEDPVAIKIAELLENVTLIHKPVSLQPRGLINKGNWCYINATLQALVACPPMYHLMKFIPLYSKVQRPCTSTPMIDSFVRLMNEFTNMPVPPKPRQALGDKIVRDIRPGAAFEPTYIYRLLTVNKSSLSEKGRQEDAEEYLGFILNGLHEEMLNLKKLLSPSNEKLTISNGPKNHSVNEEEQEEQGEGSEDEWEQVGPRNKTSVTRQADFVQTPITGIFGGHIRSVVYQQSSKESATLQPFFTLQLDIQSDKIRTVQDALESLVARESVQGYTTKTKQEVEISRRVTLEKLPPVLVLHLKRFVYEKTGGCQKLIKNIEYPVDLEISKELLSPGVKNKNFKCHRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRIDDQTVKVINQYQVVKPTAERTAYLLYYRRVDLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites