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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Delta(14)-sterol reductase LBR
Summary
- UniProt ID
- Q14739
- Gene Symbol
-
- LBR
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cholesterol biosynthesis
- Cytoplasm
- DNA-binding
- Disease variant
- Dwarfism
- Endoplasmic reticulum
- Nucleus
- Oxidoreductase
- Phosphoprotein
- Receptor
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| neutrophil differentiation |
| cholesterol biosynthetic process |
| ergosterol biosynthetic process |
| GO Term |
|---|
| nucleus |
| nuclear envelope |
| cytoplasm |
| membrane |
| nuclear membrane |
| endoplasmic reticulum membrane |
| nuclear inner membrane |
| GO Term |
|---|
| RNA binding |
| DNA binding |
| delta14-sterol reductase activity |
| lamin binding |
| chromo shadow domain binding |
| NADPH binding |
Sequence
MPSRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELKENDIKPLTSFRQRKGGSTSSSPSRRRGSRSRSRSRSPGRPPKSARRSASASHQADIKEARREVEVKLTPLILKPFGNSISRYNGEPEHIERNDAPHKNTQEKFSLSQESSYIATQYSLRPRREEVKLKEIDSKEEKYVAKELAVRTFEVTPIRAKDLEFGGVPGVFLIMFGLPVFLFLLLLMCKQKDPSLLNFPPPLPALYELWETRVFGVYLLWFLIQVLFYLLPIGKVVEGTPLIDGRRLKYRLNGFYAFILTSAVIGTSLFQGVEFHYVYSHFLQFALAATVFCVVLSVYLYMRSLKAPRNDLSPASSGNAVYDFFIGRELNPRIGTFDLKYFCELRPGLIGWVVINLVMLLAEMKIQDRAVPSLAMILVNSFQLLYVVDALWNEEALLTTMDIIHDGFGFMLAFGDLVWVPFIYSFQAFYLVSHPNEVSWPMASLIIVLKLCGYVIFRGANSQKNAFRKNPSDPKLAHLKTIHTSTGKNLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILPYFYIIYFTMLLVHREARDEYHCKKKYGVAWEKYCQRVPYRIFPYIY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 33 |
|
|||
| 34 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CDC42 GTPase cycle | Homo sapiens |
| Cholesterol biosynthesis | Homo sapiens |
| Initiation of Nuclear Envelope (NE) Reformation | Homo sapiens |
| RAC1 GTPase cycle | Homo sapiens |
| RAC2 GTPase cycle | Homo sapiens |
| RAC3 GTPase cycle | Homo sapiens |
| RHOA GTPase cycle | Homo sapiens |
| RHOC GTPase cycle | Homo sapiens |
| RHOD GTPase cycle | Homo sapiens |
| RHOG GTPase cycle | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
