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Guidelines
MIRAGE
Signal transducer and activator of transcription 4
Summary
- UniProt ID
- Q14765
- Gene Symbol
-
- STAT4
- Gene ID
- 6775
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Activator
- Cytoplasm
- DNA-binding
- Disease variant
- Nucleus
- Phosphoprotein
- Reference proteome
- SH2 domain
- Systemic lupus erythematosus
- Transcription regulation
- Gene Ontology (GO)
| GO Term |
|---|
| chromatin |
| cytoplasm |
| nucleoplasm |
| cytosol |
| nucleus |
| RNA polymerase II transcription regulator complex |
Sequence
MSQWNQVQQLEIKFLEQVDQFYDDNFPMEIRHLLAQWIENQDWEAASNNETMATILLQNLLIQLDEQLGRVSKEKNLLLIHNLKRIRKVLQGKFHGNPMHVAVVISNCLREERRILAAANMPVQGPLEKSLQSSSVSERQRNVEHKVAAIKNSVQMTEQDTKYLEDLQDEFDYRYKTIQTMDQSDKNSAMVNQEVLTLQEMLNSLDFKRKEALSKMTQIIHETDLLMNTMLIEELQDWKRRQQIACIGGPLHNGLDQLQNCFTLLAESLFQLRRQLEKLEEQSTKMTYEGDPIPMQRTHMLERVTFLIYNLFKNSFVVERQPCMPTHPQRPLVLKTLIQFTVKLRLLIKLPELNYQVKVKASIDKNVSTLSNRRFVLCGTNVKAMSIEESSNGSLSVEFRHLQPKEMKSSAGGKGNEGCHMVTEELHSITFETQICLYGLTIDLETSSLPVVMISNVSQLPNAWASIIWYNVSTNDSQNLVFFNNPPPATLSQLLEVMSWQFSSYVGRGLNSDQLHMLAEKLTVQSSYSDGHLTWAKFCKEHLPGKSFTFWTWLEAILDLIKKHILPLWIDGYVMGFVSKEKERLLLKDKMPGTFLLRFSESHLGGITFTWVDHSESGEVRFHSVEPYNKGRLSALPFADILRDYKVIMAENIPENPLKYLYPDIPKDKAFGKHYSSQPCEVSRPTERGDKGYVPSVFIPISTIRSDSTEPHSPSDLLPMSPSVYAVLRENLSPTTIETAMKSPYSAE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 735 |
|
|||
| 736 |
|
|||
| 739 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | Homo sapiens |
| Interleukin-12 signaling | Homo sapiens |
| Interleukin-20 family signaling | Homo sapiens |
| Interleukin-21 signaling | Homo sapiens |
| Interleukin-23 signaling | Homo sapiens |
| Interleukin-35 Signalling | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080745 | polymyositis | |
| DOID:0081373 | disabling pansclerotic morphea | |
| DOID:10223 | dermatomyositis | |
| DOID:12236 | primary biliary cholangitis | |
| DOID:12297 | Vogt-Koyanagi-Harada disease | |
| DOID:12894 | Sjogren's syndrome | |
| DOID:13241 | Behcet's disease | |
| DOID:1577 | limited scleroderma | |
| DOID:1580 | diffuse scleroderma | |
| DOID:1996 | rectum adenocarcinoma |
