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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Transmembrane glycoprotein NMB
Summary
- UniProt ID
- Q14956
- Gene Symbol
-
- GPNMB
- HGFIN
- NMB
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Amyloidosis
- Cell membrane
- Disease variant
- Endosome
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| early endosome membrane |
| plasma membrane |
| membrane |
| melanosome membrane |
| GO Term |
|---|
| heparin binding |
| syndecan binding |
| receptor ligand activity |
| integrin binding |
| chemoattractant activity |
Sequence
MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYPVWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNCRNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTLGQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFVTMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVNHTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLELSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSIPTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTSTLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKGLSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 350 |
|
|||
| 459 | N-linked (GlcNAc...) asparagine |
|
||
| 467 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G43417UB
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PTK6 promotes HIF1A stabilization | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050646 | distal arthrogryposis | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0060680 | pigment dispersion syndrome | |
| DOID:0060891 | Parkinson's disease 19A | |
| DOID:0060895 | Parkinson's disease 4 | |
| DOID:0060896 | Parkinson's disease 23 | |
| DOID:0080001 | bone disease | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080348 | Alzheimer's disease 1 |
