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Twist-related protein 1

Summary

UniProt ID

Q15672

Gene Symbol

BHLHA38
TWIST
TWIST1

Gene ID

7291

Organism

Homo sapiens (human)

External Links

PubChem: Q15672
The O-GlcNAc Database: Q15672
Re-Glyco: Q15672

Annotation

Keyword

3D-structure
Activator
Biological rhythms
Craniosynostosis
DNA-binding
Developmental protein
Differentiation
Disease variant
Myogenesis
Nucleus
Reference proteome
Repressor
Transcription regulation

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
chromatin
nucleus
nucleoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 55 in total

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GO Term
in utero embryonic development
neuron migration
neural tube closure
positive regulation of gene expression
positive regulation of cell migration
regulation of bone mineralization
developmental process
negative regulation of apoptotic process
positive regulation of angiogenesis
rhythmic process

Displaying entries **1 - 10** of 11 in total

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GO Term
DNA-binding transcription factor binding
cis-regulatory region sequence-specific DNA binding
DNA-binding transcription repressor activity
E-box binding
RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
transcription coregulator binding
protein domain specific binding
protein homodimerization activity
histone deacetylase binding

Annotation information from UniProt.

Sequence

MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
6	G49108TO	The O-GlcNAc Database
7	G49108TO	The O-GlcNAc Database
31	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Interleukin-4 and Interleukin-13 signaling	Homo sapiens
Nuclear events stimulated by ALK signaling in cancer	Homo sapiens
Regulation of RUNX2 expression and activity	Homo sapiens
Transcriptional regulation by RUNX2	Homo sapiens

Disease

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0080538	Sweeney-Cox syndrome	Alliance of Genome Resources
DOID:12960	acrocephalosyndactylia	Alliance of Genome Resources
DOID:14768	Saethre-Chotzen syndrome	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:2340	craniosynostosis	Alliance of Genome Resources
DOID:3459	breast carcinoma	Alliance of Genome Resources