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Twist-related protein 1

Summary

UniProt ID

Q15672

Gene Symbol

TWIST1
BHLHA38
TWIST

Organism

Homo sapiens (human)

External Links

GlyGen: Q15672
PubChem: Q15672
The O-GlcNAc Database: Q15672

Annotation

Keyword

3D-structure
Activator
Biological rhythms
Craniosynostosis
DNA-binding
Developmental protein
Differentiation
Disease variant
Myogenesis
Nucleus
Reference proteome
Repressor
Transcription regulation

Gene Ontology (GO)

Displaying entries **1 - 10** of 55 in total

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GO Term
muscle organ development
positive regulation of gene expression
positive regulation of cell migration
developmental process
positive regulation of angiogenesis
positive regulation of epithelial cell proliferation
embryonic camera-type eye formation
cell proliferation involved in heart valve development
positive regulation of epithelial to mesenchymal transition
negative regulation of macrophage cytokine production

Displaying **all 3** entries
GO Term
nucleoplasm
chromatin
nucleus

Displaying entries **1 - 10** of 11 in total

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GO Term
cis-regulatory region sequence-specific DNA binding
transcription coregulator binding
histone deacetylase binding
E-box binding
DNA-binding transcription factor binding
protein domain specific binding
protein homodimerization activity
bHLH transcription factor binding
RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific

Annotation information from UniProt.

Sequence

MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
6	G49108TO	GlyGen The O-GlcNAc Database
7	G49108TO	GlyGen The O-GlcNAc Database
31	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Interleukin-4 and Interleukin-13 signaling	Homo sapiens
Nuclear events stimulated by ALK signaling in cancer	Homo sapiens
Regulation of RUNX2 expression and activity	Homo sapiens
Transcriptional regulation by RUNX2	Homo sapiens