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MIRAGE
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
Summary
- UniProt ID
- Q15750
- Gene Symbol
-
- MAP3K7IP1
- TAB1
- Gene ID
- 10454
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasm
- Endoplasmic reticulum
- Glycoprotein
- Membrane
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| protein-containing complex |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| cytosol |
| endosome membrane |
| nuclear speck |
Sequence
MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVVTAP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 46 |
|
|||
| 52 |
|
|||
| 163 |
|
|||
| 376 |
|
|
||
| 391 |
|
|||
| 395 | O-linked (GlcNAc) serine | |||
| 396 |
|
|||
| 399 |
|
|||
| 400 |
|
|||
| 401 |
|
G49108TO
G70994MS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ALPK1 signaling pathway | Homo sapiens |
| CLEC7A (Dectin-1) signaling | Homo sapiens |
| FCERI mediated NF-kB activation | Homo sapiens |
| IRAK2 mediated activation of TAK1 complex | Homo sapiens |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | Homo sapiens |
| Interleukin-1 signaling | Homo sapiens |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | Homo sapiens |
| NOD1/2 Signaling Pathway | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
| TAK1-dependent IKK and NF-kappa-B activation | Homo sapiens |
