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TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

Summary

UniProt ID

Q15750

Gene Symbol

TAB1
MAP3K7IP1

Organism

Homo sapiens (human)

External Links

GlyGen: Q15750
PubChem: Q15750
The O-GlcNAc Database: Q15750
O-GlcNAcAtlas: Q15750

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Endoplasmic reticulum
Glycoprotein
Membrane
Phosphoprotein
Reference proteome
Ubl conjugation

Gene Ontology (GO)

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GO Term
positive regulation of protein serine/threonine kinase activity
positive regulation of cGAS/STING signaling pathway
heart morphogenesis
transforming growth factor beta receptor signaling pathway
positive regulation of MAPK cascade
cardiac septum development
coronary vasculature development
aorta development
non-canonical NF-kappaB signal transduction
in utero embryonic development

Displaying **all 7** entries
GO Term
endosome membrane
nuclear speck
endoplasmic reticulum
endoplasmic reticulum membrane
cytosol
cytoplasm
protein-containing complex

Displaying **all 5** entries
GO Term
mitogen-activated protein kinase p38 binding
protein serine/threonine phosphatase activity
protein serine/threonine kinase activator activity
protein-containing complex binding
molecular adaptor activity

Annotation information from UniProt.

Sequence

MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVVTAP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	GlyTouCan ID	Source
403	G49108TO	The O-GlcNAc Database
406	G49108TO	The O-GlcNAc Database
423	G49108TO	GlyGen The O-GlcNAc Database
450	G49108TO	GlyGen The O-GlcNAc Database
502	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 15** of 15 in total

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Pathway Name	Organism
TICAM1,TRAF6-dependent induction of TAK1 complex	Homo sapiens
TNFR1-induced NF-kappa-B signaling pathway	Homo sapiens
TRAF6-mediated induction of TAK1 complex within TLR4 complex	Homo sapiens
Ub-specific processing proteases	Homo sapiens
activated TAK1 mediates p38 MAPK activation	Homo sapiens