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Transcription factor E2F4
Summary
- UniProt ID
- Q16254
- Gene Symbol
-
- E2F4
- Gene ID
- 1874
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Cell cycle
- Cilium biogenesis/degradation
- DNA-binding
- Nucleus
- Phosphoprotein
- Reference proteome
- Transcription regulation
- Gene Ontology (GO)
| GO Term |
|---|
| RNA polymerase II transcription regulator complex |
| chromatin |
| cytoplasm |
| nucleoplasm |
Sequence
MAEAGPQAPPPPGTPSRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYDITNVLEGIGLIEKKSKNSIQWKGVGPGCNTREIADKLIELKAEIEELQQREQELDQHKVWVQQSIRNVTEDVQNSCLAYVTHEDICRCFAGDTLLAIRAPSGTSLEVPIPEGLNGQKKYQIHLKSVSGPIEVLLVNKEAWSSPPVAVPVPPPEDLLQSPSAVSTPPPLPKPALAQSQEASRPNSPQLTPTAVPGSAEVQGMAGPAAEITVSGGPGTDSKDSGELSSLPLGPTTLDTRPLQSSALLDSSSSSSSSSSSSSNSNSSSSSGPNPSTSFEPIKADPTGVLELPKELSEIFDPTRECMSSELLEELMSSEVFAPLLRLSPPPGDHDYIYNLDESEGVCDLFDVPVLNL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 14 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cyclin A:Cdk2-associated events at S phase entry | Homo sapiens |
| Cyclin D associated events in G1 | Homo sapiens |
| Cyclin E associated events during G1/S transition | Homo sapiens |
| G0 and Early G1 | Homo sapiens |
| G1/S-Specific Transcription | Homo sapiens |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | Homo sapiens |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | Homo sapiens |
| Transcription of E2F targets under negative control by DREAM complex | Homo sapiens |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3883 | Lynch syndrome |
